Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 3/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3392062 | 0.85 | KCNH2 (0.54) | KCNH2FFAR1METAP2METAP1TGFBR1 | |
| SCHEMBL3395600 | 0.80 | L3MBTL1 (0.35) | KCNH2FFAR1METAP2METAP1TGFBR1 | |
| SCHEMBL3392272 | 0.78 | KCNH2 (0.54) | KCNH2FFAR1METAP2METAP1TGFBR1 | |
| SCHEMBL3393341 | 0.76 | KCNH2 (0.43) | KCNH2FFAR1METAP2METAP1TGFBR1 | |
| SCHEMBL3395407 | 0.75 | KCNH2 (0.40) | KCNH2EGLN2LRRK2OXTR | |
| SCHEMBL24791485 | 0.75 | KCNH2 (0.53) | KCNH2FFAR1METAP2METAP1TGFBR1 | |
| SCHEMBL30872068 | 0.75 | KCNH2 (0.53) | KCNH2FFAR1METAP2METAP1TGFBR1 | |
| SCHEMBL3397575 | 0.74 | KCNH2 (0.43) | KCNH2TGFBR1EGLN2DRD1OXTR | |
| SCHEMBL13426919 | 0.73 | KCNH2 (0.53) | KCNH2FFAR1METAP2METAP1TGFBR1 | |
| SCHEMBL3433177 | 0.72 | KCNH2 (0.36) | KCNH2LRRK2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |