SCHEMBL3392437

SCHEMBL3392437

CC(C)(N)CCNC(N)=O

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 1/20 0.38
TSHR P16473 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
MAPK1 P28482 1/20 0.32
SIGMAR1 Q99720 1/20 0.31
MTNR1A P48039 1/20 0.31
POLB P06746 1/20 0.31
GGT1 P19440 1/20 0.30
MLYCD O95822 1/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21678029 0.86 GRM4 (0.35) GRM4TSHRTDP1MAPK1POLB
SCHEMBL902119 0.83 EPHX1 (0.39) GRM4SIGMAR1GGT1MLYCD
SCHEMBL10678827 0.83 GRM4 (0.39) GRM4SIGMAR1GGT1MLYCD
SCHEMBL6562473 0.83 SIGMAR1 (0.43) TSHRTDP1SIGMAR1MTNR1AMLYCD
SCHEMBL27257379 0.82 GAA (0.36) GRM4
SCHEMBL4077716 0.81 GRM4 (0.38) GRM4SIGMAR1GGT1MLYCD
Hydrochloric Acid SCHEMBL29537198 0.81 SIGMAR1 (0.42) TSHRTDP1SIGMAR1MTNR1AMLYCD
SCHEMBL15270731 0.79 MLYCD (0.36) TSHRTDP1SIGMAR1MTNR1APOLB
SCHEMBL28029861 0.77 TSHR (0.33) TSHRTDP1
SCHEMBL6602897 0.76 ALDH1A1 (0.34) GRM4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106397730-A Tertiary amine composition and method for making the composition 气体产品与化学公司 2017-02-15 CN claimed
CN-103635257-B Reducing emissions in polyurethane foam 气体产品与化学公司 2017-02-15 CN claimed
CN-104755518-A Amine catalysts for improving the stability of polyurethane systems with halogen-containing blowing agents AIR PROD & CHEM 2015-07-01 CN claimed
EP-1630185-B2 Process of manufacture of polyurethane slabstock foam BASF SE (DE) 2010-12-22 EP claimed
EP-1512707-B1 Open celled rigid polyurethane foams BASF SE (DE) 2009-09-30 EP claimed
EP-1630185-B1 Process of manufacture of polyurethane slabstock foam BASF AG (DE) 2008-02-20 EP claimed
CN-1232556-C Acid capped amine catalyst for preparing polyurethane AIR PROD & CHEM (US) 2005-12-21 CN claimed
EP-1075553-B1 ZINC AND ZINC ALLOY ELECTROPLATING ADDITIVES AND ELECTROPLATING METHODS MACDERMID PLC (GB) 2004-05-12 EP claimed
CN-1380347-A Acid capped amine catalyst for preparing polyurethane AIR PROD & CHEM (US) 2002-11-20 CN claimed
EP-1075553-A2 ZINC AND ZINC ALLOY ELECTROPLATING ADDITIVES AND ELECTROPLATING METHODS MacDermid Plc (GB) 2001-02-14 EP claimed
WO-2000050669-A2 ZINC AND ZINC ALLOY ELECTROPLATING ADDITIVES AND ELECTROPLATING METHODS MACDERMID CANNINC PLC (GB) 2000-08-31 WO claimed
US-20250163205-A1 USE OF RECYCLED POLYOL FROM AMINE-BASED HYDROLYSIS PROCESS TO PRODUCE PU FOAM EVONIK OPERATIONS GMBH (DE) 2025-05-22 US disclosed
EP-4482885-A1 USE OF RECYCLED POLYOL FROM AMINE-BASED HYDROLYSIS PROCESS TO PRODUCE PU FOAM Evonik Operations GmbH (DE) 2025-01-01 EP disclosed
CN-118742583-A Production of PU foams using recycled polyols from amine-based hydrolysis processes 赢创运营有限公司 2024-10-01 CN disclosed
US-20240309145-A1 PRODUCTION OF PU FOAMS EVONIK OPERATIONS GMBH (DE) 2024-09-19 US disclosed
CN-1235964-A Carbodiimides based on 1, 3-bis (1-methyl-1-isocyanatoethyl) benzene BASF AG (DE) 1999-11-24 CN disclosed
US-5873911-A IMPROVED WET FASTNESS OF DYEINGS ON HYDROPHILIC FIBERS CLARIANT FINANCE (BVI) LIMITED (VG) 1999-02-23 US disclosed
CN-1204346-A Process for preparing self-releasing, compact or cellular moulded bodies optionally containing reinforcing agents and made of polyisocyanate polyaddition products and internal mould release agents BASF AG (DE) 1999-01-06 CN disclosed
CN-1179440-A Storage-stable, flame retardant-containing polyol component BASF AG (DE) 1998-04-22 CN disclosed
CN-1173508-A Preparation of polyurethanes having improved curing BASF AG (DE) 1998-02-18 CN disclosed