Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | YWHAG | P61981 | 1/20 | 0.32 |
| ▸ | YWHAZ | P63104 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | PNPO | Q9NVS9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3392576 | 0.74 | P2RX2 (0.53) | ESR1PTGS1ACP1PDE4AP2RX1 | |
| SCHEMBL2692050 | 0.72 | P2RX2 (0.56) | ESR1PTGS1ACP1PDE4AP2RX1 | |
| SCHEMBL9628183 | 0.71 | ESR1 (0.33) | ESR1PTGS1ACP1PDE4AP2RX1 | |
| SCHEMBL3800949 | 0.71 | P2RX2 (0.54) | ESR1PTGS1ACP1PDE4AP2RX1 | |
| Pyridoxal Phosphate Anhydrous SCHEMBL4440488 | 0.70 | ESR1 (0.78) | ESR1PTGS1ACP1PDE4AP2RX1 | |
| SCHEMBL4318040 | 0.69 | ESR1 (0.37) | ESR1PTGS1ACP1PDE4AP2RX1 | |
| Pyridoxal Phosphate Anhydrous SCHEMBL10338098 | 0.67 | P2RX2 (0.71) | ESR1PTGS1ACP1PDE4AP2RX1 | |
| SCHEMBL14125380 | 0.66 | ESR1 (0.40) | ESR1PTGS1ACP1PDE4AP2RX1 | |
| SCHEMBL4576456 | 0.65 | ESR1 (0.52) | ESR1PTGS1ACP1PDE4AP2RX1 | |
| SCHEMBL14687825 | 0.65 | KDM4E (0.53) | ESR1PTGS1ACP1PDE4AP2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128121-A | Metal chelate compounds, tissue/organ specific | NYCOMED AS (NO) | 1992-07-07 | — | — | US | disclosed |