Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RRM2 | P31350 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 4/20 | 0.38 |
| ▸ | NOS1 | P29475 | 4/20 | 0.38 |
| ▸ | NOS2 | P35228 | 4/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.35 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7481545 | 1.00 | RRM2 (0.45) | RRM2NOS3NOS1NOS2P4HTM | |
| SCHEMBL30404501 | 0.77 | LMNA (0.38) | P4HTMKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL2642450 | 0.77 | KMT2A (0.50) | RRM2P4HTMKDM4EMEN1ALDH1A1 | |
| SCHEMBL16938675 | 0.77 | LOXL2 (0.50) | RRM2P4HTMLOXL2ABATF10 | |
| Hydrochloric Acid SCHEMBL6485768 | 0.76 | KMT2A (0.49) | RRM2P4HTMKDM4EMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6482968 | 0.76 | KMT2A (0.49) | RRM2P4HTMKDM4EMEN1ALDH1A1 | |
| SCHEMBL30404980 | 0.75 | KDM4E (0.39) | P4HTMF10KDM4EMEN1ALDH1A1 | |
| SCHEMBL1483912 | 0.75 | ADRA2A (0.47) | KDM4EMEN1MAPTKMT2ATDP1 | |
| SCHEMBL17394925 | 0.75 | KDM1A (0.40) | KDM4EPKMKMT2AL3MBTL1 | |
| SCHEMBL13783338 | 0.75 | KDM1A (0.40) | KDM4EPKMKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169318-A1 | PRODRUGS OF THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000061577-A1 | PRODRUGS OF THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-19 | — | — | WO | disclosed |