Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3388686 | 0.89 | SIGLEC9 (0.35) | MALT1GPR119NPBWR1MCHR1MAPK14 | |
| SCHEMBL3394279 | 0.88 | MALT1 (0.37) | MALT1GPR119NPBWR1MCHR1MAPK13 | |
| SCHEMBL3392854 | 0.84 | MAPK13 (0.52) | MAPK13MAPK14BRAFPTK2 | |
| SCHEMBL4602779 | 0.83 | MAPK13 (0.45) | MAPK13MAPK14PTK2 | |
| SCHEMBL3170675 | 0.82 | NPY2R (0.35) | MALT1NPBWR1MCHR1MAPK13MAPK14 | |
| SCHEMBL3390558 | 0.80 | MAPK13 (0.40) | GPR119MAPK13MAPK14BRAF | |
| SCHEMBL3390581 | 0.78 | P2RY12 (0.37) | MAPK14PTK2 | |
| SCHEMBL4603475 | 0.75 | MAPK14 (0.40) | MAPK13MAPK14PTK2 | |
| SCHEMBL3392530 | 0.75 | MAPK13 (0.56) | MAPK13MAPK14BRAFPTK2 | |
| SCHEMBL3388683 | 0.75 | MAPK14 (0.46) | MAPK13MAPK14BRAFPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943243-B1 | KINASE INHIBITORS | LILLY CO ELI (US) | 2010-12-29 | — | — | EP | disclosed |