Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.37 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602536 | 0.92 | FAAH (0.38) | MAPK14MAPTTP53SMN1; SMN2LMNA | |
| SCHEMBL2953750 | 0.91 | MAPK14 (0.40) | MAPK14MAPTLMNATSHRMAPK13 | |
| SCHEMBL3393213 | 0.87 | PTK2B (0.38) | MAPK14SMN1; SMN2LMNATSHRALOX12 | |
| SCHEMBL4602779 | 0.87 | MAPK13 (0.45) | MAPK14MAPTSMN1; SMN2MAPK13MAPK12 | |
| SCHEMBL4602880 | 0.87 | MAPK14 (0.43) | MAPK14MAPTPOLBMAPK13MAPK12 | |
| SCHEMBL4602876 | 0.86 | MAPK14 (0.42) | MAPK14MAPTPOLBSMN1; SMN2LMNA | |
| SCHEMBL4603471 | 0.82 | MAPK14 (0.61) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL3392100 | 0.80 | PTK2B (0.39) | MAPK14LMNATSHRALOX12MAPK13 | |
| SCHEMBL3393224 | 0.80 | GBA1 (0.38) | MAPK14SMN1; SMN2LMNATSHRALOX12 | |
| SCHEMBL4604375 | 0.80 | MAPK14 (0.66) | MAPK14MAPK13MAPK12MAPK11MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761520-B1 | KINASE INHIBITORS | LILLY CO ELI (US) | 2008-07-09 | — | — | EP | disclosed |