Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | EIF4E | P06730 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3393634 | 0.86 | KCNH2 (0.39) | MAPTKMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL3392940 | 0.85 | LMNA (0.41) | MAPTKMT2AMEN1KCNH2LMNA | |
| SCHEMBL3394274 | 0.85 | KCNH2 (0.43) | MAPTKMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL3392062 | 0.82 | KCNH2 (0.54) | KCNH2LRRK2TGFBR1 | |
| SCHEMBL3432960 | 0.81 | KCNH2 (0.43) | KCNH2LRRK2 | |
| Hydrochloric Acid SCHEMBL3432843 | 0.81 | KCNH2 (0.42) | KCNH2LRRK2 | |
| SCHEMBL3395952 | 0.80 | KCNH2 (0.56) | MAPTKMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL3434686 | 0.79 | KCNH2 (0.44) | KCNH2ALDH1A1MAPK1LRRK2 | |
| SCHEMBL3396008 | 0.79 | TNIK (0.43) | KCNH2 | |
| SCHEMBL3426389 | 0.79 | KCNH2 (0.43) | KMT2AMEN1RAB9ANPC1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |