Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3392940 | 0.91 | LMNA (0.41) | KCNH2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL3432960 | 0.87 | KCNH2 (0.43) | KCNH2TNIKEGLN2DRD1GCGR | |
| SCHEMBL3426389 | 0.86 | KCNH2 (0.43) | KCNH2NPC1MEN1KMT2ARAB9A | |
| SCHEMBL3396008 | 0.86 | TNIK (0.43) | KCNH2TNIKEGLN2DRD1EGLN1 | |
| SCHEMBL3395956 | 0.86 | MAPT (0.41) | KCNH2MAPTNPC1PKMMEN1 | |
| Hydrochloric Acid SCHEMBL3432843 | 0.86 | KCNH2 (0.42) | KCNH2TNIKEGLN2DRD1GCGR | |
| SCHEMBL3434686 | 0.81 | KCNH2 (0.44) | KCNH2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3395604 | 0.80 | KCNH2 (0.43) | KCNH2ALDH1A1 | |
| SCHEMBL3427227 | 0.80 | KCNH2 (0.42) | KCNH2TNIKEGLN2DRD1 | |
| SCHEMBL3392062 | 0.80 | KCNH2 (0.54) | KCNH2EGLN2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |