Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1375787 | 0.84 | KMT2A (0.59) | KMT2ASMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL27615959 | 0.84 | KMT2A (0.56) | KMT2ASMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL15801114 | 0.83 | MAPT (0.71) | KMT2ASMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL17669252 | 0.83 | MAPT (0.71) | KMT2ASMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL1482373 | 0.82 | KMT2A (0.59) | KMT2ASMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL14013923 | 0.81 | HRH3 (0.57) | KMT2ASMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL3396020 | 0.81 | REV1 (0.59) | KMT2AALDH1A1MAPTMEN1MAPK1 | |
| SCHEMBL21872349 | 0.81 | KMT2A (0.58) | KMT2ASMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL11736036 | 0.79 | DRD2 (0.60) | KMT2AALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL1372140 | 0.78 | MAPT (0.66) | KMT2ASMN1; SMN2ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015703-A2 | NOVEL 6-O-SUBSTITUTED 15-MEMBERED 8A- AND 9A-LACTAMS | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) | 2010-02-11 | — | — | WO | disclosed |