Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REV1 | Q9UBZ9 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8002247 | 0.86 | REV1 (0.62) | REV1MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL5114345 | 0.85 | REV1 (0.65) | REV1MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL8576314 | 0.83 | REV1 (0.59) | REV1MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL4179915 | 0.83 | REV1 (0.59) | REV1MAPTALDH1A1MAPK1LMNA | |
| Hydrochloric Acid SCHEMBL1373922 | 0.83 | REV1 (0.63) | REV1MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL4179918 | 0.83 | GAA (0.60) | REV1MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL31053565 | 0.81 | REV1 (0.68) | REV1MAPTALDH1A1LMNAGAA | |
| SCHEMBL3393191 | 0.81 | KMT2A (0.56) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL20271748 | 0.80 | ALDH1A1 (0.56) | REV1MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL14207945 | 0.80 | REV1 (0.67) | REV1MAPTALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015703-A2 | NOVEL 6-O-SUBSTITUTED 15-MEMBERED 8A- AND 9A-LACTAMS | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) | 2010-02-11 | — | — | WO | disclosed |