Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.48 |
| ▸ | RELA | Q04206 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL989648 | 0.74 | AR (0.46) | TP53KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL867080 | 0.73 | RAB9A (0.50) | SMN1; SMN2RAB9ANPC1LMNANFKB1 | |
| SCHEMBL30466255 | 0.73 | RAB9A (0.50) | SMN1; SMN2RAB9ANPC1LMNANFKB1 | |
| SCHEMBL339597 | 0.73 | RAB9A (0.49) | SMN1; SMN2RAB9ANPC1LMNANFKB1 | |
| SCHEMBL2245316 | 0.70 | RAB9A (0.58) | SMN1; SMN2RAB9ANPC1LMNANFKB1 | |
| SCHEMBL30429916 | 0.70 | RAB9A (0.58) | SMN1; SMN2RAB9ANPC1LMNANFKB1 | |
| SCHEMBL20855087 | 0.70 | ALDH1A1 (0.54) | SMN1; SMN2RAB9ANPC1LMNANFKB1 | |
| SCHEMBL1006314 | 0.68 | AR (0.42) | TP53KDM4EMAPTALDH1A1HSD17B10 | |
| SCHEMBL3073946 | 0.68 | RAB9A (0.69) | SMN1; SMN2RAB9ANPC1LMNANFKB1 | |
| SCHEMBL14632640 | 0.68 | ESR1 (0.38) | LMNAKDM4EKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016092-A1 | Catalysts based on quinoline precursors | BASELL POLYOLEFINE GMBH (DE) | 2012-01-19 | — | — | US | disclosed |
| US-20120016092-A1 | Catalysts based on quinoline precursors | BASELL POLYOLEFINE GMBH (DE) | 2012-01-19 | — | — | US | disclosed |