Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.49 |
| ▸ | NPC1 | O15118 | 10/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL867080 | 0.82 | RAB9A (0.50) | RAB9ANPC1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL30466255 | 0.82 | RAB9A (0.50) | RAB9ANPC1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL2245316 | 0.79 | RAB9A (0.58) | RAB9ANPC1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL30429916 | 0.79 | RAB9A (0.58) | RAB9ANPC1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL3073946 | 0.76 | RAB9A (0.69) | RAB9ANPC1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL8617042 | 0.74 | KDM4E (0.64) | RAB9ANPC1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL30353950 | 0.74 | KDM4E (0.64) | RAB9ANPC1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL339359 | 0.73 | SMN1; SMN2 (0.48) | RAB9ANPC1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL827403 | 0.72 | RAB9A (0.67) | RAB9ANPC1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL15229057 | 0.72 | PARP1 (0.54) | RAB9ANPC1KDM4ESMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009369-A1 | CATALYSTS BASED ON QUINOLINE PRECURSORS | BASELL POLYOLEFINE GMBG (DE) | 2012-01-19 | — | — | WO | disclosed |
| US-20120016092-A1 | Catalysts based on quinoline precursors | BASELL POLYOLEFINE GMBH (DE) | 2012-01-19 | — | — | US | disclosed |
| US-20120016092-A1 | Catalysts based on quinoline precursors | BASELL POLYOLEFINE GMBH (DE) | 2012-01-19 | — | — | US | disclosed |