Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 1.00 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 5/20 | 0.60 |
| ▸ | CA2 | P00918 | 5/20 | 0.60 |
| ▸ | EGFR | P00533 | 3/20 | 0.51 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25442713 | 0.82 | HKDC1 (0.70) | ALOX5HKDC1CA1CA2EGFR | |
| SCHEMBL17912677 | 0.78 | GPR84 (0.64) | ALOX5HKDC1CA1CA2RAB9A | |
| SCHEMBL3394005 | 0.77 | ALOX5 (0.62) | ALOX5EGFRNOX4HIF1AALDH1A1 | |
| SCHEMBL5794016 | 0.77 | HKDC1 (1.00) | ALOX5HKDC1CA1CA2EGFR | |
| SCHEMBL17912639 | 0.75 | HDAC6 (0.71) | ALOX5HKDC1CA1CA2HIF1A | |
| SCHEMBL18415526 | 0.74 | CA1 (1.00) | ALOX5CA1CA2HIF1AALDH1A1 | |
| SCHEMBL13830817 | 0.74 | CA1 (0.62) | ALOX5HKDC1CA1CA2EGFR | |
| SCHEMBL498241 | 0.73 | HKDC1 (0.73) | ALOX5HKDC1CA1CA2EGFR | |
| SCHEMBL6262049 | 0.72 | CA1 (0.72) | ALOX5HKDC1CA1CA2HIF1A | |
| SCHEMBL13934091 | 0.72 | CA1 (0.87) | ALOX5HKDC1CA1CA2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033906-A2 | EFFICIENT INDUCTION OF PLURIPOTENT STEM CELLS USING SMALL MOLECULE COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-03-25 | — | — | WO | disclosed |