SCHEMBL517353

SCHEMBL517353

C=CC(=O)C(N)(CN)C(=O)C=C

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
TSHR P16473 2/20 0.36
FGFR4 P22455 1/20 0.36
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3394150 0.79 ALDH1A1 (0.37) ALDH1A1TSHRFGFR4LMNA
SCHEMBL3394157 0.74 ALDH1A1 (0.36) ALDH1A1TSHRFGFR4LMNA
SCHEMBL6118788 0.73 FDPS (0.38) ALDH1A1TSHRLMNA
SCHEMBL7187535 0.72
SCHEMBL3578262 0.72 ALDH1A1 (0.36) ALDH1A1TSHRFGFR4LMNA
SCHEMBL30895615 0.72 SMN1; SMN2 (0.32) ALDH1A1TSHRFGFR4LMNA
SCHEMBL21553166 0.71 ODC1 (0.39) ALDH1A1TSHRLMNA
SCHEMBL21553167 0.71 ODC1 (0.39) ALDH1A1TSHRLMNA
SCHEMBL21979219 0.70 SMN1; SMN2 (0.31) LMNA
SCHEMBL12501681 0.70 SMN1; SMN2 (0.31) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2263 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120082241-A Polymer gel environment-friendly asphalt isolating agent and preparation method thereof 河海大学 2025-06-03 CN claimed
CN-117772162-A Chromatography medium for removing polyphenol substances and preparation method thereof 西安蓝晓科技新材料股份有限公司 2024-03-29 CN claimed
CN-113999573-A Water-based paint and preparation method and application thereof 亚士防水科技(滁州)有限公司 2022-02-01 CN claimed
CN-113502042-B Nano reinforced modified polyester and preparation method thereof 苏州瀚海新材料有限公司 2021-11-26 CN claimed
EP-3484908-A1 NON-NUCLEOSIDIC SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE SYNTHESIS AM Chemicals Llc (US) 2019-05-22 EP claimed
WO-2018013999-A1 NON-NUCLEOSIDIC SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE SYNTHESIS AM CHEMICALS LLC (US) 2018-01-18 WO claimed
EP-1343802-B1 PROCESS FOR THE PREPARATION OF OLIGONUCLEOTIDES AVECIA BIOTECHNOLOGY INC (US) 2012-05-30 EP claimed
EP-2332954-A2 Process for the preparation of phosphorothionate oligonucleotides Avecia Biotechnology, Inc. (US) 2011-06-15 EP claimed
WO-2010037402-A1 MOLECULAR VACCINES FOR INFECTIOUS DISEASE DAKO DENMARK A/S (DK) 2010-04-08 WO claimed
WO-2007110624-A2 IMMOBILISED REAGENT UNIVERSITY COURT OF THE UNIVERSITY OFEDINBURGH (GB) 2007-10-04 WO claimed
WO-2005123971-A2 SCAVENGER SUPPORTS WITH AMINO-FUNCTIONALISED PENDANT KETOESTER OR KETOMIDE GROUPS FOR REMOVING METALS FROM SOLUTIONS REAXA LIMITED (GB) 2005-12-29 WO claimed
US-6768005-B2 GENERATION OF PREFERENTIAL OLIGONUCLEOTIDES; GENERATE SOLID SUPPORT, INCUBATE WITH OLIGONUCLEOTIDES, ATTACH OLIGONUCLELOTIDE TO SOLID SUPPORT, EXPOSE TO ACETONITRILE, RECOVER ADJUSTED OLIGONUCLEOTIDE AVECIA LIMITED (GB) 2004-07-27 US claimed
US-20030229221-A1 Process for the preparation of phosphorothioate oligonucleotides AVECIA LIMITED (GB) 2003-12-11 US claimed
EP-1343802-A2 PROCESS FOR THE PREPARATION OF PHOSPHOROTHIONATE OLIGONUCLEOTIDES Avecia Limited (GB) 2003-09-17 EP claimed
US-20020111479-A1 Generation of preferential oligonucleotides; generate solid support, incubate with oligonucleotides, attach oligonuclelotide to solid support, expose to acetonitrile, recover adjusted oligonucleotide WELLS FARGO BANK, NATIONAL ASSOCIATION 2002-08-15 US claimed
EP-1224193-A1 PROCESS FOR THE PREPARATION OF PHOSPHOROTHIOATE TRIESTERS AND OLIGONUCLEOTIDES Avecia Limited (GB) 2002-07-24 EP claimed
WO-2002046205-A2 PROCESS FOR THE PREPARATION OF PHOSPHOROTHIONATE OLIGONUCLEOTIDES AVECIA LIMITED (GB) 2002-06-13 WO claimed
WO-2002034380-A1 A METHOD AND APPARATUS FOR FACILE MANIPULATION OF SPATIALLY ADDRESSED SOLID SUPPORTS FOR COMBINATORIAL CHEMICAL SYNTHESIS BARNES SEEMAN DAVID (US) 2002-05-02 WO claimed
WO-2001027126-A1 PROCESS FOR THE PREPARATION OF PHOSPHOROTHIOATE TRIESTERS AND OLIGONUCLEOTIDES AVECIA LIMITED (GB) 2001-04-19 WO claimed
US-4593073-A Hydrophilic backbone bonded with a arginine or lysine compound THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARING (MCGILL UNIV.) (CA) 1986-06-03 US claimed