Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.58 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.58 |
| ▸ | TAS1R2 | Q8TE23 | 5/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510673 | 0.78 | P2RX7 (0.69) | TAS1R3TAS1R1TAS1R2RECQLNPC1 | |
| SCHEMBL3391180 | 0.78 | P2RX7 (0.69) | TAS1R3TAS1R1TAS1R2RECQLNPC1 | |
| SCHEMBL20860900 | 0.77 | TAS1R3 (0.76) | TAS1R3TAS1R1TAS1R2RECQLHTT | |
| SCHEMBL701434 | 0.74 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2RECQLHTT | |
| SCHEMBL701435 | 0.74 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2RECQLHTT | |
| SCHEMBL14335326 | 0.74 | TAS1R3 (0.71) | TAS1R3TAS1R1TAS1R2RECQLHTT | |
| SCHEMBL14335704 | 0.74 | TAS1R3 (0.71) | TAS1R3TAS1R1TAS1R2RECQLHTT | |
| SCHEMBL14335714 | 0.74 | TAS1R3 (0.71) | TAS1R3TAS1R1TAS1R2RECQLHTT | |
| SCHEMBL20990440 | 0.72 | ALDH1A1 (0.74) | HTTTSHRALDH1A1LMNA | |
| SCHEMBL659023 | 0.72 | ALDH1A1 (0.74) | HTTTSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370530-B1 | ACYLATED 1,2,3,4-TETRAHYDRONAPHTHYL AMINES AND THEIR USE AS PHARMACEUTICAL | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-12-29 | — | — | EP | disclosed |