Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3336330 | 0.88 | KIF11 (0.60) | KIF11POLBSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL3435307 | 0.88 | KIF11 (0.76) | KIF11POLBMAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL5341216 | 0.85 | KIF11 (1.00) | KIF11POLBMAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL3398148 | 0.85 | PDE1C (0.57) | KIF11POLBMAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL13426160 | 0.82 | TP53 (0.74) | KIF11POLBMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3399002 | 0.80 | KIF11 (0.60) | KIF11POLBMAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL3391291 | 0.80 | KIF11 (0.63) | KIF11ALDH1A1GAAADORA2BPKM | |
| SCHEMBL13426241 | 0.79 | KIF11 (0.60) | KIF11POLBSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL13426223 | 0.79 | KIF11 (0.60) | KIF11POLBSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL3341613 | 0.79 | KIF11 (0.62) | KIF11POLBSMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |