Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3396805 | 0.99 | TNIK (0.51) | POLBTNIKCSNK2A2CSNK2A1MCHR1 | |
| SCHEMBL3394470 | 0.92 | HIF1A (0.52) | ALDH1A1MAPTRAB9AKMT2AAURKB | |
| SCHEMBL3397267 | 0.90 | BRD4 (0.52) | POLBMCHR1AURKB | |
| SCHEMBL3397141 | 0.86 | CSNK2A2 (0.51) | POLBTNIKCSNK2A2CSNK2A1ALDH1A1 | |
| SCHEMBL3393212 | 0.86 | TNIK (0.56) | POLBTNIKCSNK2A2CSNK2A1ALDH1A1 | |
| SCHEMBL3397155 | 0.84 | CSNK2A2 (0.60) | POLBCSNK2A2CSNK2A1ALDH1A1ALOX15 | |
| SCHEMBL3393897 | 0.83 | TNIK (0.49) | POLBTNIKCSNK2A2CSNK2A1ALDH1A1 | |
| SCHEMBL3393589 | 0.82 | PKM (0.56) | TNIKCSNK2A2CSNK2A1MAPTRAB9A | |
| SCHEMBL3396383 | 0.81 | CSNK2A2 (0.55) | POLBCSNK2A2CSNK2A1ALDH1A1MAPT | |
| SCHEMBL3394878 | 0.81 | TNIK (0.75) | TNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216795-A1 | TNIK INHIBITOR AND THE USE | YAMADA TESSHI | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216795-A1 | TNIK INHIBITOR AND THE USE | TNIK, TNNI3K, TNK1 | POLB 4627/4885TNIK 1/4885CSNK2A2 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.