Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | KIT | P10721 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 2/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.50 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.48 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.48 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3392722 | 0.86 | RAB9A (0.67) | KMT2AHSD17B10TNIKMAPTMAPK14 | |
| SCHEMBL3397155 | 0.84 | CSNK2A2 (0.60) | KMT2AMAPK14CSNK2A2CSNK2A1NPC1 | |
| SCHEMBL3396383 | 0.83 | CSNK2A2 (0.55) | KMT2AMAPTL3MBTL1MAPK14CSNK2A2 | |
| SCHEMBL3397267 | 0.83 | BRD4 (0.52) | FLT3 | |
| SCHEMBL28668646 | 0.82 | PKM (0.79) | PKMHIF1AEPAS1KMT2AHSD17B10 | |
| SCHEMBL3394786 | 0.82 | POLB (0.52) | KMT2ATNIKMAPTL3MBTL1CSNK2A2 | |
| SCHEMBL15667669 | 0.81 | TNIK (0.67) | PKMHIF1AEPAS1KMT2AHSD17B10 | |
| SCHEMBL3392647 | 0.81 | TNIK (0.77) | TNIKIKBKETBK1 | |
| SCHEMBL3396805 | 0.81 | TNIK (0.51) | KMT2ATNIKMAPTCSNK2A2CSNK2A1 | |
| SCHEMBL3394470 | 0.80 | HIF1A (0.52) | HIF1AEPAS1KMT2AFLT3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216795-A1 | TNIK INHIBITOR AND THE USE | YAMADA TESSHI | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216795-A1 | TNIK INHIBITOR AND THE USE | TNIK, TNNI3K, TNK1 | PKM 3077/4885HIF1A 2555/4885EPAS1 2729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.