Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 3/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3393346 | 0.80 | HSP90AA1 (0.59) | DHFRHSP90AA1HSP90AB1ALDH1A1MAPT | |
| SCHEMBL3396593 | 0.78 | KDM4E (0.45) | HSP90AA1HSP90AB1ALDH1A1MAPTNPC1 | |
| SCHEMBL5471286 | 0.78 | GSK3B (0.60) | DHFRHSP90AA1HSP90AB1KMT2AMEN1 | |
| SCHEMBL3399081 | 0.78 | ADORA2A (0.51) | NPC1KDM4EDYRK1ACYP2D6CYP2C9 | |
| SCHEMBL3942089 | 0.77 | HSP90AA1 (0.76) | DHFRHSP90AA1HSP90AB1ADORA3KMT2A | |
| SCHEMBL2324238 | 0.76 | ADORA2A (0.62) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL2322961 | 0.75 | ADORA2A (0.50) | KMT2AALDH1A1MAPTNPC1KDM4E | |
| SCHEMBL15757214 | 0.74 | AGPAT2 (0.56) | DHFRHSP90AA1HSP90AB1ADORA3KMT2A | |
| SCHEMBL13425400 | 0.73 | GAA (0.50) | HSP90AA1HSP90AB1ADORA3KMT2AALDH1A1 | |
| SCHEMBL5327111 | 0.73 | ALDH1A1 (0.71) | KMT2AMEN1ALDH1A1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |