Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.75 |
| ▸ | CNR2 | P34972 | 2/20 | 0.75 |
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.57 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.57 |
| ▸ | TAS1R2 | Q8TE23 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6520141 | 1.00 | CNR1 (0.75) | CNR1CNR2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3390949 | 0.86 | CNR1 (1.00) | CNR1CNR2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL6515255 | 0.86 | CNR1 (1.00) | CNR1CNR2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10256809 | 0.84 | CNR1 (0.54) | CNR1CNR2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3392234 | 0.79 | MTNR1A (0.50) | CNR1CNR2HTTALDH1A1MAPT | |
| SCHEMBL3395112 | 0.79 | MTNR1A (0.50) | CNR1CNR2HTTALDH1A1MAPT | |
| SCHEMBL4815896 | 0.77 | MAPT (0.47) | CNR1CNR2HTTLMNAALDH1A1 | |
| SCHEMBL3395392 | 0.76 | CNR1 (1.00) | CNR1CNR2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3147087 | 0.76 | MAPT (0.46) | CNR1CNR2HTTLMNAALDH1A1 | |
| SCHEMBL6511967 | 0.76 | CNR1 (1.00) | CNR1CNR2TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370530-B1 | ACYLATED 1,2,3,4-TETRAHYDRONAPHTHYL AMINES AND THEIR USE AS PHARMACEUTICAL | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-12-29 | — | — | EP | disclosed |