Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PDE2A | O00408 | 2/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10246861 | 0.88 | CNR1 (0.70) | CNR1CNR2LMNATAS1R3TAS1R1 | |
| SCHEMBL3395117 | 0.84 | CNR1 (0.75) | CNR1CNR2LMNATAS1R3TAS1R1 | |
| SCHEMBL6520141 | 0.84 | CNR1 (0.75) | CNR1CNR2LMNATAS1R3TAS1R1 | |
| SCHEMBL10252477 | 0.79 | DHODH (0.54) | LMNAPDE2ATAS1R3TAS1R1KMT2A | |
| SCHEMBL10258791 | 0.77 | TAS1R3 (0.52) | LMNAPDE2ATAS1R3TAS1R1KMT2A | |
| SCHEMBL10246859 | 0.77 | LMNA (0.55) | LMNAPDE2ATAS1R3TAS1R1KMT2A | |
| SCHEMBL10246997 | 0.77 | LMNA (0.62) | LMNATAS1R3TAS1R1KMT2AMEN1 | |
| SCHEMBL10252923 | 0.76 | HDAC8 (0.57) | LMNAPDE2ATAS1R3TAS1R1KMT2A | |
| SCHEMBL10246865 | 0.75 | LMNA (0.54) | LMNATAS1R3TAS1R1KMT2AMEN1 | |
| SCHEMBL10247155 | 0.75 | LMNA (0.77) | LMNATAS1R3TAS1R1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140243335-A1 | SUBSTITUTED HYDOXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2014-08-28 | — | — | US | disclosed |
| US-20140243335-A1 | SUBSTITUTED HYDOXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2014-08-28 | — | — | US | disclosed |
| WO-2012012322-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-01-26 | — | — | WO | disclosed |
| US-20120015943-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACUTICALS, INC. (US) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015943-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | HDAC6, HDAC1, HDAC2 | CNR1 2818/4885CNR2 1904/4885LMNA 1529/4885 |
| US-20140243335-A1 | SUBSTITUTED HYDOXAMIC ACIDS AND USES THEREOF | HDAC6, HDAC1, H1-3 | CNR1 1527/4885CNR2 887/4885LMNA 2546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.