Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | PPARD | Q03181 | 2/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511965 | 1.00 | CNR1 (0.64) | CNR1ALDH1A1HPGDNPSR1SMN1; SMN2 | |
| SCHEMBL6515251 | 0.86 | CNR1 (0.61) | CNR1SMN1; SMN2GAANPC1MTNR1A | |
| SCHEMBL3390946 | 0.86 | CNR1 (0.61) | CNR1SMN1; SMN2GAANPC1MTNR1A | |
| SCHEMBL12788196 | 0.83 | SMN1; SMN2 (0.69) | CNR1ALDH1A1HPGDNPSR1SMN1; SMN2 | |
| SCHEMBL3395392 | 0.78 | CNR1 (1.00) | CNR1ALDH1A1HPGDNPSR1SMN1; SMN2 | |
| SCHEMBL6511967 | 0.78 | CNR1 (1.00) | CNR1ALDH1A1HPGDNPSR1SMN1; SMN2 | |
| SCHEMBL13071969 | 0.75 | CHRM4 (0.54) | CNR1ALDH1A1HPGDNPSR1SMN1; SMN2 | |
| SCHEMBL13407796 | 0.75 | ALDH1A1 (1.00) | CNR1ALDH1A1HPGDNPSR1SMN1; SMN2 | |
| SCHEMBL3395112 | 0.75 | MTNR1A (0.50) | CNR1ALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL3392234 | 0.75 | MTNR1A (0.50) | CNR1ALDH1A1SMN1; SMN2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370530-B1 | ACYLATED 1,2,3,4-TETRAHYDRONAPHTHYL AMINES AND THEIR USE AS PHARMACEUTICAL | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-12-29 | — | — | EP | disclosed |
| EP-1370530-A1 | ACYLATED 1,2,3,4-TETRAHYDRONAPHTHYL AMINES AND THEIR USE AS PHARMACEUTICAL | Aventis Pharma Deutschland GmbH (DE) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002064565-A1 | ACYLATED 1,2,3,4-TETRAHYDRONAPHTHYL AMINES AND THEIR USE AS PHARMACEUTICAL | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-08-22 | — | — | WO | disclosed |