SCHEMBL339548

SCHEMBL339548

O=Cc1ccc2cccc(Br)c2n1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.63
BACE1 P56817 1/20 0.53
MEN1 O00255 8/20 0.46
KMT2A Q03164 8/20 0.46
RAB9A P51151 4/20 0.46
NPC1 O15118 4/20 0.46
HSP90AA1 P07900 2/20 0.46
ALDH1A1 P00352 1/20 0.46
KDM4E B2RXH2 2/20 0.39
FGFR4 P22455 1/20 0.39
MAPKAPK2 P49137 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
HTT P42858 1/20 0.38
AR P10275 1/20 0.37
LCK P06239 1/20 0.36
TERT O14746 1/20 0.36
CD74 P04233 1/20 0.36
MIF P14174 1/20 0.36
CA12 O43570 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1977526 0.81 BACE1 (0.53) CCR1BACE1MEN1KMT2ARAB9A
SCHEMBL1088335 0.79 CCR1 (1.00) CCR1MEN1KMT2ARAB9ANPC1
SCHEMBL7443034 0.78 MEN1 (0.51) BACE1MEN1KMT2ARAB9ANPC1
SCHEMBL29406155 0.77 KDM4E (0.64) CCR1MEN1KMT2ARAB9ANPC1
SCHEMBL29694379 0.77 KDM4E (0.64) CCR1MEN1KMT2ARAB9ANPC1
SCHEMBL2134303 0.77 CCR1 (0.63) CCR1MEN1KMT2ARAB9ANPC1
SCHEMBL1716529 0.77 CCR1 (0.63) CCR1MEN1KMT2ARAB9ANPC1
SCHEMBL6176904 0.77 CCR1 (0.63) CCR1MEN1KMT2ARAB9ANPC1
SCHEMBL279696 0.77 KDM4E (0.64) CCR1MEN1KMT2ARAB9ANPC1
SCHEMBL13740612 0.76 CCR1 (0.61) CCR1MEN1KMT2ARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113666964-B Preparation and application of thioiminoquinoline metal compound 青岛科技大学 2023-03-14 CN claimed
CN-113666964-A Preparation and application of thioiminoquinoline metal compound 青岛科技大学 2021-11-19 CN claimed
EP-4701782-A1 CATALYST SYSTEM AND ETHYLENE OLIGOMERIZATION PROCESS FOR THE PREPARATION OF LINEAR ALPHA OLEFINS Chevron Phillips Chemical Company LP (US) 2026-03-04 EP disclosed
EP-4701783-A1 PHOSPHINE-IMINO-QUINOLINE AND RELATED LIGANDS FOR USE IN ETHYLENE OLIGOMERIZATION PROCESSES Chevron Phillips Chemical Company LP (US) 2026-03-04 EP disclosed
CN-118515653-B EZH2 specific inhibitor and preparation method and application thereof 西湖制药(杭州)有限公司 2024-12-10 CN disclosed
US-20240400473-A1 CATALYST SYSTEM AND ETHYLENE OLIGOMERIZATION PROCESS FOR THE PREPARATION OF LINEAR ALPHA OLEFINS CHEVRON PHILLIPS CHEMICAL COMPANY LP 2024-12-05 US disclosed
WO-2024226497-A1 CATALYST SYSTEM AND ETHYLENE OLIGOMERIZATION PROCESS FOR THE PREPARATION OF LINEAR ALPHA OLEFINS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2024-10-31 WO disclosed
US-20240360052-A1 PHOSPHINE-IMINO-QUINOLINE AND RELATED LIGANDS FOR USE IN ETHYLENE OLIGOMERIZATION PROCESSES CHEVRON PHILLIPS CHEMICAL COMPANY LP 2024-10-31 US disclosed
WO-2024226492-A1 PHOSPHINE-IMINO-QUINOLINE AND RELATED LIGANDS FOR USE IN ETHYLENE OLIGOMERIZATION PROCESSES CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2024-10-31 WO disclosed
CN-118515653-A EZH2 specific inhibitor and preparation method and application thereof 西湖制药(杭州)有限公司 2024-08-20 CN disclosed
CN-114685461-B Crown ether-containing chiral o-diamine compound and transition metal complex, chiral biaryl compound, and preparation method and application thereof 中国科学院化学研究所 2024-07-19 CN disclosed
WO-2012154274-A1 TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS ARRAY BIOPHARMA INC. (US) 2012-11-15 WO disclosed
US-20120016092-A1 Catalysts based on quinoline precursors BASELL POLYOLEFINE GMBH (DE) 2012-01-19 US disclosed
US-20120016092-A1 Catalysts based on quinoline precursors BASELL POLYOLEFINE GMBH (DE) 2012-01-19 US disclosed
WO-2012009369-A1 CATALYSTS BASED ON QUINOLINE PRECURSORS BASELL POLYOLEFINE GMBG (DE) 2012-01-19 WO disclosed
US-20110144100-A1 TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS ARRAY BIOPHARMA INC. (US) 2011-06-16 US disclosed
CN-101679422-A Imidazo[1,2-a]pyridine compounds as receptor tyrosine kinase inhibitors ARRAY BIOPHARMA INC 2010-03-24 CN disclosed
WO-2010022081-A1 TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS ARRAY BIOPHARMA INC. (US) 2010-02-25 WO disclosed
EP-1973888-A1 ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-10-01 EP disclosed
WO-2007079162-A1 ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-07-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360052-A1 PHOSPHINE-IMINO-QUINOLINE AND RELATED LIGANDS FOR USE IN ETHYLENE OLIGOMERIZATION PROCESSES PHOSPHO1, PEBP1, PPIP5K2 CCR1 3946/4885BACE1 2471/4885MEN1 206/4885
US-20110144100-A1 TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS PIM1, PIM3, PIM2 CCR1 3139/4885BACE1 3846/4885MEN1 2196/4885
US-20240400473-A1 CATALYST SYSTEM AND ETHYLENE OLIGOMERIZATION PROCESS FOR THE PREPARATION OF LINEAR ALPHA OLEFINS AP1M1, AP2M1, OXER1 CCR1 1082/4885BACE1 1039/4885MEN1 630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.