SCHEMBL339574

SCHEMBL339574

c1cc2c3c(cccc3c1)NCN2

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 15/20 0.52
KMT2A Q03164 15/20 0.52
MAPT P10636 8/20 0.52
ALDH1A1 P00352 7/20 0.52
GAA P10253 7/20 0.52
KDM4E B2RXH2 5/20 0.52
L3MBTL1 Q9Y468 3/20 0.52
APAF1 O14727 2/20 0.52
NPSR1 Q6W5P4 1/20 0.52
RAD52 P43351 1/20 0.48
HPGD P15428 5/20 0.47
HSD17B10 Q99714 4/20 0.47
TSHR P16473 4/20 0.47
NR4A1 P22736 3/20 0.47
USP2 O75604 3/20 0.47
APP P05067 2/20 0.47
SNCA P37840 2/20 0.47
HTT P42858 1/20 0.47
NPC1 O15118 2/20 0.43
CYP3A4 P08684 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7621039 0.84 CDK2 (0.42) MEN1KMT2AMAPTALDH1A1GAA
SCHEMBL28498212 0.75 RAD52 (0.54) MEN1KMT2AMAPTALDH1A1GAA
SCHEMBL30549 0.74
SCHEMBL7604368 0.73 PARP1 (0.55) MEN1KMT2AMAPTALDH1A1GAA
SCHEMBL10670210 0.71 ALOX15 (0.39) MEN1KMT2AMAPTALDH1A1GAA
Hydrochloric Acid SCHEMBL31003509 0.71 GAA (0.41) MEN1KMT2AMAPTALDH1A1GAA
SCHEMBL7502074 0.70 MEN1 (0.45) MEN1KMT2AMAPTALDH1A1GAA
SCHEMBL11699088 0.70 GRK6 (0.50) MEN1KMT2AMAPTALDH1A1GAA
SCHEMBL6932843 0.70 TSHR (0.41) MEN1KMT2AMAPTALDH1A1GAA
SCHEMBL25349480 0.69 MEN1 (0.41) MEN1KMT2AMAPTALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104418811-A 2,3-dihydronaphthalene-embedded m-diazabenzene analogue, synthetic method, drug composition and application thereof UNIV JIANGNAN 2015-03-18 CN claimed
EP-2750191-A1 Photoelectric conversion element and solid-state imaging device Fujifilm Corporation (JP) 2014-07-02 EP claimed
US-20140054577-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2014-02-27 US claimed
US-20080230123-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2008-09-25 US claimed
EP-1970959-A2 Photoelectric conversion element and solid-state imaging device FUJIFILM Corporation (JP) 2008-09-17 EP claimed
US-6756190-B2 WORKABILITY; PROCESSING STABILITY FUJI PHOTO FILM CO., LTD. (JP) 2004-06-29 US claimed
US-6733959-B2 FOR FORMING VISIBLE IMAGE EASTMAN KODAK COMPANY 2004-05-11 US claimed
US-6699647-B2 TELLURIUM CHEMICAL SENSITIZERS ADDED TO THE PHOTOTHERMOGRAPHIC EMULSION, FOR EXAMPLE TELLURIUM COMPLEXED WITH FOUR IMIDAZOLIDIN-2-THIONE GROUPS AND TWO CHLORINE ATOMS EASTMAN KODAK COMPANY 2004-03-02 US claimed
US-20040005520-A1 Silver halide color photographic light-sensitive material FUJIFILM CORPORATION (JP) 2004-01-08 US claimed
US-20030073026-A1 Chemically sensitized aqueous-based photothermographic emulsions and materials and methods of using same EASTMAN KODAK COMPANY 2003-04-17 US claimed
EP-0824718-A1 STABLE ANTIHALATION MATERIALS FOR PHOTOGRAPHIC AND PHOTOTHERMOGRAPHIC ELEMENTS Imation Corp. (US) 1998-02-25 EP claimed
EP-0512949-B1 Substituted 2,3-dihydroperimidine stabilizers CIBA GEIGY AG (CH) 1997-01-08 EP claimed
EP-0748465-A1 DIHYDROPERIMIDINE SQUARYLIUM DYES AS ANTIHALATION AND ACUTANCE MATERIALS FOR PHOTOGRAPHIC AND PHOTOTHERMOGRAPHIC ARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-12-18 EP claimed
WO-1996035142-A1 STABLE ANTIHALATION MATERIALS FOR PHOTOGRAPHIC AND PHOTOTHERMOGRAPHIC ELEMENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-11-07 WO claimed
WO-1995023357-A1 DIHYDROPERIMIDINE SQUARYLIUM DYES AS ANTIHALATION AND ACUTANCE MATERIALS FOR PHOTOGRAPHIC AND PHOTOTHERMOGRAPHIC ARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-08-31 WO claimed
US-5380635-A Light sensitive recording materials MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-01-10 US claimed
EP-0512949-A1 Substituted 2,3-dihydroperimidine stabilizers CIBA-GEIGY AG (CH) 1992-11-11 EP claimed
US-5147568-A Oil additives, oxidation and heat resistance CIBA-GEIGY CORPORATION (US) 1992-09-15 US claimed
EP-0107492-B1 HELICHROMIC-SMECTIC LIQUID CRYSTAL COMPOSITIONS AND DISPLAY CELLS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-08-09 EP claimed
US-4565424-A Asymmetric dichroic dye molecules having poly(arylazo) linking groups, a bis-substituted aryl thiazyl end group, and another end group MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-01-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080230123-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLID-STATE IMAGING DEVICE PIN4, SUN2, PIN1 MEN1 760/4885KMT2A 1120/4885MAPT 419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.