Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29832698 | 0.86 | SMN1; SMN2 (0.62) | SMN1; SMN2CHRM2KDM4EALDH1A1MEN1 | |
| SCHEMBL472123 | 0.84 | SMN1; SMN2 (0.61) | SMN1; SMN2CHRM2KDM4EALDH1A1MEN1 | |
| SCHEMBL3398272 | 0.83 | DPP7 (0.56) | SMN1; SMN2ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL1303746 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2CHRM2KDM4EALDH1A1MEN1 | |
| SCHEMBL12831873 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2CHRM2KDM4EALDH1A1MEN1 | |
| SCHEMBL13793636 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2CHRM2KDM4EALDH1A1NPC1 | |
| SCHEMBL14067286 | 0.80 | CHRM2 (0.61) | SMN1; SMN2CHRM2KDM4EALDH1A1MEN1 | |
| SCHEMBL11569803 | 0.79 | CHRM2 (0.53) | SMN1; SMN2CHRM2KDM4EALDH1A1MEN1 | |
| SCHEMBL29438821 | 0.79 | CHRM2 (0.70) | SMN1; SMN2CHRM2KDM4EALDH1A1MEN1 | |
| SCHEMBL230222 | 0.79 | CHRM2 (0.70) | SMN1; SMN2CHRM2KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015703-A2 | NOVEL 6-O-SUBSTITUTED 15-MEMBERED 8A- AND 9A-LACTAMS | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) | 2010-02-11 | — | — | WO | disclosed |