Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 5/20 | 0.38 |
| ▸ | SLC6A11 | P48066 | 5/20 | 0.38 |
| ▸ | SLC6A13 | Q9NSD5 | 5/20 | 0.38 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL652967 | 0.85 | SLC6A12 (0.46) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL12345487 | 0.85 | SLC6A12 (0.46) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL7448393 | 0.84 | CYP2D6 (0.43) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL8003132 | 0.84 | SLC6A12 (0.43) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL24064245 | 0.81 | SIGMAR1 (0.42) | ALOX5 | |
| SCHEMBL11857523 | 0.81 | SIGMAR1 (0.42) | ALOX5 | |
| SCHEMBL11857534 | 0.81 | SIGMAR1 (0.42) | ALOX5 | |
| SCHEMBL185540 | 0.81 | SIGMAR1 (0.42) | ALOX5 | |
| SCHEMBL28103618 | 0.78 | SLC6A12 (0.41) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL9504422 | 0.77 | ANPEP (0.54) | GABRR1ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2184986-A2 | PHARMACEUTICAL COMPOSITIONS FOR TREATING CHRONIC PAIN AND PAIN ASSOCIATED WITH NEUROPATHY | Trinity Laboratories, Inc. (US) | 2010-05-19 | — | — | EP | claimed |
| WO-2009021058-A2 | PHARMACEUTICAL COMPOSITIONS FOR TREATING CHRONIC PAIN AND PAIN ASSOCIATED WITH NEUROPATHY | TRINITY LABORTORIES, INC. (US) | 2009-02-12 | — | — | WO | claimed |