Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | UNG | P13051 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 5/20 | 0.38 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5951672 | 0.78 | TP53 (0.54) | ALDH1A1TDP1TSHRPTGS2 | |
| SCHEMBL15267169 | 0.75 | ACHE (0.35) | — | |
| Isophthalic Dicarboxaldehyde SCHEMBL180566 | 0.75 | ALDH1A1 (0.67) | ALDH1A1UNGCYP2A6SRCTRIM24 | |
| Isophthalic Dicarboxaldehyde SCHEMBL4952540 | 0.75 | ALDH1A1 (0.67) | ALDH1A1UNGCYP2A6SRCTRIM24 | |
| Isophthalic Dicarboxaldehyde SCHEMBL16267528 | 0.74 | ALDH1A1 (0.58) | ALDH1A1UNGCYP2A6SRCTRIM24 | |
| Isophthalic Dicarboxaldehyde SCHEMBL28611144 | 0.73 | ALDH1A1 (0.67) | ALDH1A1UNGCYP2A6SRCTRIM24 | |
| SCHEMBL340725 | 0.72 | ALDH1A1 (0.39) | ALDH1A1UNGCYP2A6SRCTRIM24 | |
| SCHEMBL996868 | 0.72 | CYP2A6 (0.52) | ALDH1A1CYP2A6TRIM24TRIM33RAB9A | |
| Isophthalic Dicarboxaldehyde SCHEMBL4304012 | 0.71 | ALDH1A1 (0.63) | ALDH1A1UNGCYP2A6SRCTRIM24 | |
| Isophthalic Dicarboxaldehyde SCHEMBL20477528 | 0.71 | ALDH1A1 (0.61) | ALDH1A1UNGCYP2A6SRCTRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1723139-B1 | CELL TARGETING CONJUGATES | PETER MACCALLUM CANCER INST (AU) | 2014-01-01 | — | — | EP | disclosed |
| US-8097238-B2 | Cell targeting conjugates | PETER MACCALLUM CANCER INSTITUTE (AU) | 2012-01-17 | — | — | US | disclosed |
| US-20070140970-A1 | Cell targeting conjugates | PETER MACCALLUM CANCER INSTITUTE | 2007-06-21 | — | — | US | disclosed |
| EP-1723139-A1 | CELL TARGETING CONJUGATES | PETER MacCALLUM CANCER INSTITUTE (AU) | 2006-11-22 | — | — | EP | disclosed |
| WO-2005082894-A1 | CELL TARGETING CONJUGATES | PETER MACCALLUM CANCER INSTITUTE (AU) | 2005-09-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070140970-A1 | Cell targeting conjugates | CD47, CD74, CD2 | ALDH1A1 1727/4885UNG 153/4885CYP2A6 3424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.