Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.45 |
| ▸ | WNT3A | P56704 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29410859 | 0.85 | LMNA (0.51) | LMNAGAACTNNB1WNT3ASMN1; SMN2 | |
| SCHEMBL2027517 | 0.85 | LMNA (0.51) | LMNAGAACTNNB1WNT3ASMN1; SMN2 | |
| SCHEMBL2489145 | 0.82 | LMNA (0.49) | LMNAGAACTNNB1WNT3ASMN1; SMN2 | |
| SCHEMBL10137791 | 0.81 | LMNA (0.55) | LMNAGAACTNNB1WNT3ACNR2 | |
| SCHEMBL4710154 | 0.79 | LMNA (0.53) | LMNAGAACTNNB1WNT3ASMN1; SMN2 | |
| SCHEMBL29256271 | 0.79 | LMNA (0.53) | LMNAGAACTNNB1WNT3ASMN1; SMN2 | |
| SCHEMBL19863249 | 0.78 | LMNA (0.51) | LMNAGAACTNNB1WNT3ACNR2 | |
| SCHEMBL31575836 | 0.78 | LMNA (0.60) | LMNAGAACTNNB1WNT3ASMN1; SMN2 | |
| SCHEMBL5635178 | 0.78 | LMNA (0.60) | LMNAGAACTNNB1WNT3ASMN1; SMN2 | |
| SCHEMBL17493298 | 0.77 | LMNA (0.44) | LMNAGAACTNNB1WNT3ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |