SCHEMBL19863249

SCHEMBL19863249

CC(C(=O)c1ccccc1C(F)(F)F)C(F)(F)F

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.51
GAA P10253 1/20 0.51
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
CTNNB1 P35222 2/20 0.43
WNT3A P56704 2/20 0.43
CNR2 P34972 2/20 0.42
CTSS P25774 2/20 0.41
TAS2R14 Q9NYV8 1/20 0.41
PTPRC P08575 1/20 0.40
PTGS1 P23219 1/20 0.40
ALDH1A1 P00352 1/20 0.40
KCNK3 O14649 1/20 0.40
KCNK9 Q9NPC2 1/20 0.40
CTSK P43235 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19863251 0.86 LMNA (0.49) LMNAGAASLC6A2SLC6A4CTNNB1
SCHEMBL10137791 0.85 LMNA (0.55) LMNAGAASLC6A2SLC6A4CTNNB1
SCHEMBL4710154 0.84 LMNA (0.53) LMNAGAASLC6A2SLC6A4CTNNB1
SCHEMBL29410859 0.82 LMNA (0.51) LMNAGAASLC6A2SLC6A4CTNNB1
SCHEMBL2027517 0.82 LMNA (0.51) LMNAGAASLC6A2SLC6A4CTNNB1
SCHEMBL19863247 0.80 HPGD (0.41) SLC6A2SLC6A4ALDH1A1
SCHEMBL3396782 0.78 LMNA (0.55) LMNAGAACTNNB1WNT3ACNR2
SCHEMBL19863244 0.77 NR4A1 (0.52) LMNACNR2ALDH1A1
SCHEMBL29256271 0.76 LMNA (0.53) LMNAGAACTNNB1WNT3ACNR2
SCHEMBL19863245 0.76 HPGD (0.48) GAAALDH1A1KCNK3KCNK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9983475-B2 Fluorinated sulfonate esters of aryl ketones for non-ionic photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-05-29 US disclosed
US-9983475-B2 Fluorinated sulfonate esters of aryl ketones for non-ionic photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-05-29 US disclosed
US-20180046077-A1 FLUORINATED SULFONATE ESTERS OF ARYL KETONES FOR NON-IONIC PHOTO-ACID GENERATORS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-02-15 US disclosed
US-20180046077-A1 FLUORINATED SULFONATE ESTERS OF ARYL KETONES FOR NON-IONIC PHOTO-ACID GENERATORS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180046077-A1 FLUORINATED SULFONATE ESTERS OF ARYL KETONES FOR NON-IONIC PHOTO-ACID GENERATORS PFAS, PLG, PPARG LMNA 381/4885GAA 1140/4885SLC6A2 4578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.