Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 8/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314004 | 1.00 | CYP11B2 (0.33) | CYP11B2MKNK1MKNK2CYP11B1FTO | |
| SCHEMBL3399894 | 0.91 | MKNK1 (0.40) | CYP11B2MKNK1MKNK2CYP11B1PIK3CG | |
| SCHEMBL316434 | 0.91 | MKNK1 (0.40) | CYP11B2MKNK1MKNK2CYP11B1PIK3CG | |
| SCHEMBL316063 | 0.90 | CHRNB1 (0.34) | CYP11B2MKNK1MKNK2CYP11B1 | |
| SCHEMBL316064 | 0.90 | CHRNB1 (0.34) | CYP11B2MKNK1MKNK2CYP11B1 | |
| SCHEMBL3401178 | 0.87 | MKNK1 (0.36) | CYP11B2MKNK1MKNK2CYP11B1PIK3CG | |
| SCHEMBL314909 | 0.87 | MKNK1 (0.36) | CYP11B2MKNK1MKNK2CYP11B1PIK3CG | |
| SCHEMBL2409364 | 0.87 | PRMT5 (0.35) | FTOCYP1A2 | |
| SCHEMBL2409361 | 0.87 | PRMT5 (0.35) | FTOCYP1A2 | |
| SCHEMBL2142952 | 0.87 | MAP4K4 (0.42) | CYP11B2MKNK1MKNK2CYP11B1PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |