Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.35 |
| ▸ | ALPL | P05186 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314909 | 1.00 | MKNK1 (0.36) | MKNK1MKNK2CYP11B1CYP11B2PIK3CG | |
| SCHEMBL2409610 | 0.89 | HSD17B1 (0.42) | MKNK1MKNK2PIK3CGPIK3CAPIK3CD | |
| SCHEMBL2409613 | 0.89 | HSD17B1 (0.42) | MKNK1MKNK2PIK3CGPIK3CAPIK3CD | |
| SCHEMBL2142952 | 0.88 | MAP4K4 (0.42) | MKNK1MKNK2CYP11B1CYP11B2PIK3CG | |
| SCHEMBL3399894 | 0.88 | MKNK1 (0.40) | MKNK1MKNK2CYP11B1CYP11B2PIK3CG | |
| SCHEMBL316434 | 0.88 | MKNK1 (0.40) | MKNK1MKNK2CYP11B1CYP11B2PIK3CG | |
| SCHEMBL314556 | 0.88 | CYP11B2 (0.32) | MKNK1MKNK2CYP11B1CYP11B2PIK3CG | |
| SCHEMBL3397066 | 0.88 | CYP11B2 (0.32) | MKNK1MKNK2CYP11B1CYP11B2PIK3CG | |
| SCHEMBL316078 | 0.88 | CYP11B2 (0.32) | MKNK1MKNK2CYP11B1CYP11B2PIK3CG | |
| SCHEMBL3399023 | 0.88 | CYP11B2 (0.32) | MKNK1MKNK2CYP11B1CYP11B2PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |