Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.32 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.31 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.31 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | INPPL1 | O15357 | 2/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314556 | 1.00 | CYP11B2 (0.32) | CYP11B2F2RCYP11B1MKNK1MKNK2 | |
| SCHEMBL3399023 | 0.89 | CYP11B2 (0.32) | CYP11B2F2RCYP11B1MKNK1MKNK2 | |
| SCHEMBL316078 | 0.89 | CYP11B2 (0.32) | CYP11B2F2RCYP11B1MKNK1MKNK2 | |
| SCHEMBL2416421 | 0.89 | F2R (0.39) | F2RNTMT1 | |
| SCHEMBL2416424 | 0.89 | F2R (0.39) | F2RNTMT1 | |
| SCHEMBL314909 | 0.88 | MKNK1 (0.36) | CYP11B2CYP11B1MKNK1MKNK2PIK3CG | |
| SCHEMBL3393977 | 0.88 | PIK3C3 (0.31) | CYP11B2CYP11B1DYRK1AGSK3B | |
| SCHEMBL314743 | 0.88 | PIK3C3 (0.31) | CYP11B2CYP11B1DYRK1AGSK3B | |
| SCHEMBL3401178 | 0.88 | MKNK1 (0.36) | CYP11B2CYP11B1MKNK1MKNK2PIK3CG | |
| SCHEMBL3400937 | 0.87 | CYP11B2 (0.34) | CYP11B2CYP11B1DYRK1APIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |