SCHEMBL3397084

SCHEMBL3397084

CCO[Si](CCc1ccc(C)cc1)(OCC)OCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.43
CYP2A6 P11509 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43
AGXT P21549 2/20 0.38
CYP4F2 P78329 1/20 0.37
CYP4A11 Q02928 1/20 0.37
IDO1 P14902 1/20 0.37
KCNH2 Q12809 4/20 0.36
HRH3 Q9Y5N1 1/20 0.36
IGF1R P08069 1/20 0.35
ALOX15 P16050 1/20 0.35
MAPT P10636 1/20 0.35
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
KMT2A Q03164 1/20 0.33
CHKA P35790 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL167111 0.92 CYP4F2 (0.37) CYP1A2CYP2A6TAAR1CYP4F2CYP4A11
SCHEMBL27094921 0.86 HRH3 (0.39) CYP4F2CYP4A11HRH3MAPTRAB9A
SCHEMBL12458731 0.84 CYP4F2 (0.33) TAAR1CYP4F2CYP4A11
SCHEMBL15794165 0.83 KMT2A (0.44) MAPTNPC1SMN1; SMN2MEN1ALDH1A1
SCHEMBL12458723 0.82 CYP4F2 (0.33) CYP4F2CYP4A11
SCHEMBL9908451 0.82 CA2 (0.48) TAAR1IDO1ALDH1A1KMT2A
SCHEMBL12458720 0.82 CYP4F2 (0.33) CYP4F2CYP4A11
SCHEMBL2399132 0.82 CALM1 (0.33) CYP4F2CYP4A11MEN1ALDH1A1KMT2A
SCHEMBL8960954 0.82 GFER (0.48) CYP1A2TAAR1ALDH1A1
SCHEMBL929637 0.82 CYP4F2 (0.33) CYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3055359-B1 TREATED FILLERS, COMPOSITIONS CONTAINING SAME, AND ARTICLES PREPARED THEREFROM PPG IND OHIO INC (US) 2023-06-07 EP claimed
EP-3055361-B1 TREATED FILLERS, COMPOSITIONS CONTAINING SAME, AND ARTICLES PREPARED THEREFROM PPG IND OHIO INC (US) 2023-06-07 EP claimed
EP-3055360-B1 TREATED FILLERS, COMPOSITIONS CONTAINING SAME, AND ARTICLES PREPARED THEREFROM PPG IND OHIO INC (US) 2021-06-23 EP claimed
EP-3055362-B1 TREATED FILLERS COMPOSITIONS CONTAINING SAME, AND ARTICLES PREPARED THEREFROM PPG IND OHIO INC (US) 2021-04-21 EP claimed
US-10882927-B2 Treated fillers, compositions containing same, and articles prepared therefrom PPG INDUSTRIES OHIO, INC. (US) 2021-01-05 US claimed
US-10882928-B2 Treated fillers, compositions containing same, and articles prepared therefrom PPG INDUSTRIES OHIO, INC. (US) 2021-01-05 US claimed
CN-105764999-B Treated fillers, compositions containing the same, and articles prepared therefrom PPG工业俄亥俄公司 2020-07-07 CN claimed
US-10066032-B2 Treated fillers, compositions containing same, and articles prepared therefrom PPG INDUSTRIES OHIO, INC. (US) 2018-09-04 US claimed
US-20170283590-A1 Treated Fillers, Compositions Containing Same, and Articles Prepared Therefrom QEMETICA S.A. (PL) 2017-10-05 US claimed
US-20170283591-A1 Treated Fillers, Compositions Containing Same, and Articles Prepared Therefrom QEMETICA S.A. (PL) 2017-10-05 US claimed
WO-2015054118-A1 TREATED FILLERS, COMPOSITIONS CONTAINING SAME, AND ARTICLES PREPARED THEREFROM PPG INDUSTRIES OHIO, INC. (US) 2015-04-16 WO claimed
WO-2015054116-A1 TREATED FILLERS, COMPOSITIONS CONTAINING SAME, AND ARTICLES PREPARED THEREFROM PPG INDUSTRIES OHIO, INC. (US) 2015-04-16 WO claimed
WO-2015054114-A1 TREATED FILLERS, COMPOSITIONS CONTAINING SAME, AND ARTICLES PREPARED THEREFROM PPG INDUSTRIES OHIO, INC. (US) 2015-04-16 WO claimed
WO-2015054107-A1 TREATED FILLERS, COMPOSITIONS CONTAINING SAME, AND ARTICLES PREPARED THEREFROM PPG INDUSTRIES OHIO, INC. (US) 2015-04-16 WO claimed
US-20150099826-A1 Treated Fillers, Compositions Containing Same, and Articles Prepared Therefrom PPG INDUSTRIES OHIO, INC. 2015-04-09 US claimed
US-20150099824-A1 Treated Fillers, Compositions Containing Same, and Articles Prepared Therefrom PPG INDUSTRIES OHIO, INC. 2015-04-09 US claimed
US-20150099825-A1 Treated Fillers, Compositions Containing Same, and Articles Prepared Therefrom QEMETICA S.A. (PL) 2015-04-09 US claimed
US-8846806-B2 Treated fillers, compositions containing same, and articles prepared therefrom PPG INDUSTRIES OHIO, INC. (US) 2014-09-30 US claimed
CN-103890105-A TREATED FILLERS, COMPOSITIONS CONTAINING SAME, AND ARTICLES PREPARED THEREFROM PPG IND OHIO INC 2014-06-25 CN claimed
US-20130079445-A1 TREATED FILLERS, COMPOSITIONS CONTAINING SAME, AND ARTICLES PREPARED THEREFROM QEMETICA S.A. (PL) 2013-03-28 US claimed