1-Nitropyrene

1-Nitropyrene

SCHEMBL339725

O=[N+]([O-])c1ccc2ccc3cccc4ccc1c2c34

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.57
TDP1 Q9NUW8 4/20 0.54
CYP3A4 P08684 4/20 0.53
HSD17B10 Q99714 4/20 0.53
ALOX15 P16050 1/20 0.53
HPRT1 P00492 1/20 0.49
KMT2A Q03164 3/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
GAA P10253 2/20 0.46
MEN1 O00255 2/20 0.46
HPGD P15428 4/20 0.45
TSHR P16473 3/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
CTSB P07858 1/20 0.44
CYP1A2 P05177 4/20 0.44
CYP1A1 P04798 1/20 0.44
CYP1B1 Q16678 1/20 0.44
KDM4E B2RXH2 2/20 0.43
MAPT P10636 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Nitropyrene SCHEMBL29450697 1.00 ALDH1A1 (0.57) ALDH1A1TDP1CYP3A4HSD17B10ALOX15
1-Nitropyrene SCHEMBL28378090 0.98 ALDH1A1 (0.55) ALDH1A1TDP1CYP3A4HSD17B10ALOX15
1-Nitropyrene SCHEMBL28892009 0.96 ALDH1A1 (0.53) ALDH1A1TDP1CYP3A4HSD17B10ALOX15
1-Nitropyrene SCHEMBL28624685 0.94 ALDH1A1 (0.52) ALDH1A1TDP1CYP3A4HSD17B10ALOX15
Pyrene SCHEMBL28292596 0.93 HPRT1 (0.51) ALDH1A1TDP1CYP3A4HSD17B10ALOX15
SCHEMBL29450698 0.92 TDP1 (0.50) ALDH1A1TDP1CYP3A4HSD17B10ALOX15
SCHEMBL1804954 0.92 TDP1 (0.50) ALDH1A1TDP1CYP3A4HSD17B10ALOX15
SCHEMBL967910 0.92 TDP1 (0.50) ALDH1A1TDP1CYP3A4HSD17B10ALOX15
1-Nitropyrene SCHEMBL8019945 0.90 ALDH1A1 (0.47) ALDH1A1TDP1CYP3A4HSD17B10ALOX15
SCHEMBL28796982 0.89 HPRT1 (0.51) ALDH1A1TDP1CYP3A4HSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 735 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119662249-A Preparation method and application of carbon dots for detecting thiophanate methyl 中南大学 2025-03-21 CN claimed
CN-113930236-B Fluorescent sensor based on layered double hydroxide, pyrene-containing graphene oxide composite material, preparation method and application thereof 福建省海凝环保科技有限公司 2024-11-05 CN claimed
CN-118890950-A Graphene oxide PN junction and preparation method and application thereof 中国矿业大学(北京) 2024-11-01 CN claimed
CN-116212873-B Alumina-supported copper heterogeneous catalyst with molecular imprinting function and preparation method and application thereof 中国科学院兰州化学物理研究所 2024-10-29 CN claimed
CN-113711007-B Method for determining generation source of microparticles in atmosphere 株式会社岛津制作所 2024-10-25 CN claimed
CN-117843516-B Photoinitiator applicable to KrF photoresist, preparation method and photoresist composition 上海艾深斯科技有限公司 2024-05-28 CN claimed
CN-117843516-A Photoinitiator applicable to KrF photoresist, preparation method and photoresist composition 上海艾深斯科技有限公司 2024-04-09 CN claimed
CN-116212873-A Alumina-supported copper heterogeneous catalyst with molecular imprinting function and preparation method and application thereof 中国科学院兰州化学物理研究所 2023-06-06 CN claimed
CN-116072855-A Silicon-carbon negative electrode material and preparation method thereof 中国科学院成都有机化学有限公司 2023-05-05 CN claimed
CN-113117078-B Novel tumor treatment drug AuNCs @ GTTN and preparation method and application thereof 上海大学 2023-03-17 CN claimed
US-5663030-A A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT XEROX CORPORATION (US) 1997-09-02 US claimed
EP-0337698-B1 Photosensitive Polymer CHISSO CORP (JP) 1993-11-10 EP claimed
EP-0337698-A2 Photosensitive Polymer Chisso Corporation (JP) 1989-10-18 EP claimed
US-4859611-A Affinity column and process for detection of low molecular weight toxic substances MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1989-08-22 US claimed
EP-0232167-B1 PHOTOSENSITIVE AND HIGH ENERGY BEAM SENSITIVE RESIN COMPOSITION CONTAINING SUBSTITUTED POLYSILOXANE NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1988-12-28 EP claimed
US-4702990-A Photosensitive resin composition and process for forming photo-resist pattern using the same NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1987-10-27 US claimed
EP-0232167-A2 Photosensitive and high energy beam sensitive resin composition containing substituted polysiloxane NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1987-08-12 EP claimed
EP-0196787-A1 Process for detection of aflatoxins Trustees of Boston University (US) 1986-10-08 EP claimed
US-4522913-A DIACRYLATE OR LOW MOLECULAR WEIGHT OLIGOMER THEROF, POLYMERIC FILLER, AND SENSITTIZER DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1985-06-11 US claimed
US-3984378-A PHOTOCONDUCTIVE FILMS KABUSHIKI KAISHA RICOH (JA) 1976-10-05 US claimed