Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | GAA | P10253 | 4/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.72 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.71 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3391307 | 0.89 | MEN1 (0.79) | MEN1KMT2AGAAPDE1CADORA2B | |
| SCHEMBL3398354 | 0.88 | MEN1 (0.64) | MEN1KMT2AGAAMAPK1PDE1C | |
| SCHEMBL3397010 | 0.87 | KIF11 (0.76) | MEN1KMT2AGAAMAPK1PDE1C | |
| SCHEMBL10112951 | 0.85 | HSD17B10 (0.76) | GAAMAPK1HSD17B10ALDH1A1ALOX15 | |
| SCHEMBL3435823 | 0.82 | MEN1 (0.65) | MEN1KMT2AGAAPDE1CADORA2B | |
| SCHEMBL13425331 | 0.81 | MEN1 (0.67) | MEN1KMT2AGAAPDE1CADORA2B | |
| SCHEMBL13425510 | 0.81 | PDE1C (0.74) | MEN1KMT2AGAAMAPK1PDE1C | |
| SCHEMBL3395577 | 0.81 | PDE1C (0.82) | MEN1KMT2AGAAMAPK1PDE1C | |
| SCHEMBL10112947 | 0.80 | HSD17B10 (0.69) | KMT2AGAAMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL3393104 | 0.79 | PDE1C (0.79) | MEN1KMT2AGAAMAPK1PDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |