Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KIF11 | P52732 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5351543 | 0.87 | KIF11 (0.66) | KMT2AGAAADORA2BTDP1TP53 | |
| SCHEMBL3391307 | 0.87 | MEN1 (0.79) | MEN1KMT2APDE1CGAAADORA2B | |
| SCHEMBL3397010 | 0.82 | KIF11 (0.76) | MEN1KMT2APDE1CGAAADORA2B | |
| SCHEMBL3397385 | 0.81 | MEN1 (0.81) | MEN1KMT2APDE1CGAAADORA2B | |
| SCHEMBL13425510 | 0.81 | PDE1C (0.74) | MEN1KMT2APDE1CGAAADORA2B | |
| SCHEMBL8479802 | 0.81 | ALDH1A1 (0.59) | MEN1KMT2AGAANPSR1 | |
| SCHEMBL3395577 | 0.80 | PDE1C (0.82) | MEN1KMT2APDE1CGAAADORA2B | |
| SCHEMBL3393104 | 0.79 | PDE1C (0.79) | MEN1KMT2APDE1CGAAADORA2B | |
| SCHEMBL3396126 | 0.78 | PDE1C (0.69) | MEN1KMT2APDE1CGAAADORA2B | |
| SCHEMBL3435823 | 0.78 | MEN1 (0.65) | MEN1KMT2APDE1CGAAADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |