SCHEMBL3397604

SCHEMBL3397604

NC(=O)SC1CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20623601 0.86 EPHX1 (0.41)
SCHEMBL11784109 0.86 EPHX1 (0.41)
SCHEMBL529492 0.71
SCHEMBL11688999 0.69
SCHEMBL3058000 0.65
SCHEMBL31631279 0.63
SCHEMBL3075371 0.61 CES2 (0.41)
Urea SCHEMBL28062092 0.58 TDP1 (0.50)
Urea SCHEMBL8582182 0.57
SCHEMBL277846 0.56 EPHX1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114671864-B Heteroaryl substituted pyridines and methods of use 艾伯维公司 2025-04-08 CN claimed
EP-0498179-B1 Cyclopropancarboxylic acid amides and thioamides, process and intermediates for their preparation and their use as pesticides BASF AG (DE) 1996-09-25 EP claimed
EP-0412391-B1 CYCLOPROPANE THIOCARBOXYLIC ACID AMIDES BASF Aktiengesellschaft (DE) 1993-09-29 EP claimed
US-5190963-A Pesticides, crop protection BASF AKTIENGESELLSCHAFT (DE) 1993-03-02 US claimed
US-5132326-A Insecticides which interfere with hormonal activity BASF AKTIENGESELLSCHAFT (DE) 1992-07-21 US claimed
JP-10114737-A None JP disclosed
JP-3135953-A None JP disclosed
JP-4338379-A None JP disclosed
CN-114671864-B Heteroaryl substituted pyridines and methods of use 艾伯维公司 2025-04-08 CN disclosed
CN-119707763-A Method for synthesizing thioamide 广东莱佛士制药技术有限公司 2025-03-28 CN disclosed
CN-115003655-B Cycloalkyl urea derivatives 住友制药株式会社 2025-03-21 CN disclosed
WO-2024213089-A1 SUBSTITUTED DIHYDROTHIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海壹迪生物技术有限公司 2024-10-17 WO disclosed
EP-0674513-A4 1995-10-25 EP disclosed
EP-0674513-A1 RETROVIRAL PROTEASE INHIBITING COMPOUNDS. ABBOTT LAB (US) 1995-10-04 EP disclosed
WO-1994014436-A1 RETROVIRAL PROTEASE INHIBITING COMPOUNDS ABBOTT LABORATORIES (US) 1994-07-07 WO disclosed
US-5190963-A Pesticides, crop protection BASF AKTIENGESELLSCHAFT (DE) 1993-03-02 US disclosed
US-5190963-A Pesticides, crop protection BASF AKTIENGESELLSCHAFT (DE) 1993-03-02 US disclosed
JP-H04338379-A CYCLOPROPANE(THIO)CARBOXAMIDE BASF AG 1992-11-25 JP disclosed
US-5132326-A Insecticides which interfere with hormonal activity BASF AKTIENGESELLSCHAFT (DE) 1992-07-21 US disclosed
JP-H03135953-A CYCLOPROPANETHIOCARBOXAMIDES BASF AG 1991-06-10 JP disclosed