Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.56 |
| ▸ | PPARG | P37231 | 7/20 | 0.56 |
| ▸ | PPARD | Q03181 | 7/20 | 0.56 |
| ▸ | PPARA | Q07869 | 7/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TLR2 | O60603 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | FABP4 | P15090 | 2/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9290873 | 1.00 | GPR84 (0.56) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL9291138 | 1.00 | GPR84 (0.56) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL9290884 | 1.00 | GPR84 (0.56) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL338706 | 0.98 | AKR1B1 (0.54) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL339162 | 0.92 | GABBR2 (0.57) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL8844692 | 0.86 | GPR84 (0.58) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL8844642 | 0.86 | GPR84 (0.58) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL8844655 | 0.86 | GPR84 (0.58) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL8844686 | 0.86 | GPR84 (0.58) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL5984044 | 0.85 | LPAR3 (0.71) | LPAR3LPAR2CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097753-B2 | Mixtures composed or monocarboxy-functionalized dialkylphosphinic acids, their use and a process for their preparation | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-01-17 | — | — | US | disclosed |
| EP-1832594-B1 | Compounds of mono-carboxyl functionalised dialkylphosphine acid salts, a method for their manufacture and their application | CLARIANT FINANCE BVI LTD (VG) | 2011-05-18 | — | — | EP | disclosed |
| EP-1832596-B1 | Compounds of mono-carboxyl functionalised dialkylphosphine acids and other components | CLARIANT FINANCE BVI LTD (VG) | 2011-01-26 | — | — | EP | disclosed |
| US-7485745-B2 | Mixtures composed of monocarboxy-functionalized dialkylphosphinic esters and of further components | CLARIANT INTERNATIONAL LTD. (CH) | 2009-02-03 | — | — | US | disclosed |
| US-20070213436-A1 | Mixtures composed or monocarboxy-functionalized dialkylphosphinic acids, their use and a process for their preparation | CLARIANT INTERNATIONAL LTD | 2007-09-13 | — | — | US | disclosed |
| US-20070210288-A1 | Mixtures composed of monocarboxy-functionalized dialkylphosphinic esters and of further components | CLARIANT INTERNATIONAL LTD | 2007-09-13 | — | — | US | disclosed |
| EP-1832596-A1 | Compounds of mono-carboxyl functionalised dialkylphosphine acids and other components | CLARIANT INTERNATIONAL LTD. (CH) | 2007-09-12 | — | — | EP | disclosed |
| EP-1832594-A1 | Compounds of mono-carboxyl functionalised dialkylphosphine acid salts, a method for their manufacture and their application | CLARIANT INTERNATIONAL LTD. (CH) | 2007-09-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213436-A1 | Mixtures composed or monocarboxy-functionalized dialkylphosphinic acids, their use and a process for their preparation | PAH, ALKBH3, FTO | GPR84 487/4885PPARG 1550/4885PPARD 2100/4885 |
| US-20070210288-A1 | Mixtures composed of monocarboxy-functionalized dialkylphosphinic esters and of further components | ALKBH3, FFAR3, EBP | GPR84 221/4885PPARG 530/4885PPARD 1534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.