Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL722516 | 0.71 | KMT2A (0.39) | MEN1ALDH1A1KMT2A | |
| SCHEMBL716873 | 0.62 | NPC1 (0.47) | MEN1ALDH1A1HTTKMT2A | |
| SCHEMBL20526971 | 0.59 | LMNA (0.42) | MEN1ALDH1A1HTTKMT2A | |
| SCHEMBL717463 | 0.59 | KMT2A (0.44) | MEN1ALDH1A1KMT2A | |
| SCHEMBL29659605 | 0.55 | ABCB1 (0.44) | KMT2A | |
| SCHEMBL19670017 | 0.55 | ALDH1A1 (0.49) | ALDH1A1HTT | |
| SCHEMBL38651179 | 0.55 | — | — | |
| SCHEMBL1942607 | 0.55 | ABCB1 (0.40) | MEN1ALDH1A1HTTKMT2A | |
| SCHEMBL7732631 | 0.54 | EPHX2 (0.35) | MEN1ALDH1A1HTTKMT2A | |
| SCHEMBL22380056 | 0.54 | ACHE (0.38) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2251326-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2010-11-17 | — | — | EP | disclosed |