Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339891 | 0.90 | DPP4 (0.39) | CNR2DPP4ALDH1A1DPP8DPP9 | |
| SCHEMBL339638 | 0.87 | CNR2 (0.44) | CNR2PDE10AALDH1A1 | |
| SCHEMBL339388 | 0.86 | DPP4 (0.43) | CNR2DPP4DPP8DPP9 | |
| SCHEMBL339832 | 0.79 | DPP4 (0.49) | DPP4DPP8DPP9 | |
| SCHEMBL338879 | 0.78 | KDM4E (0.37) | CNR2ALDH1A1 | |
| SCHEMBL367649 | 0.77 | CNR2 (0.53) | CNR2DPP4PDE10AALDH1A1 | |
| SCHEMBL340301 | 0.77 | DPP4 (0.40) | DPP4ALDH1A1DPP8DPP9 | |
| SCHEMBL339289 | 0.75 | DPP4 (0.46) | CNR2DPP4DPP8DPP9 | |
| SCHEMBL339025 | 0.71 | DPP4 (0.48) | CNR2DPP4ALDH1A1DPP8DPP9 | |
| SCHEMBL338923 | 0.70 | CYP11B2 (0.34) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077787-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2012-03-29 | — | — | US | disclosed |
| US-20120077787-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2012-03-29 | — | — | US | disclosed |
| US-20120077787-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2012-03-29 | — | — | US | disclosed |
| US-8097617-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-01-17 | — | — | US | disclosed |
| US-8097617-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-01-17 | — | — | US | disclosed |
| US-8097617-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-01-17 | — | — | US | disclosed |
| US-20090253689-A1 | Organic Compounds | NOVARTIS AG (CH) | 2009-10-08 | — | — | US | disclosed |
| US-20090253689-A1 | Organic Compounds | NOVARTIS AG (CH) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077787-A1 | ORGANIC COMPOUNDS | OAT, GPR119, OTC | CNR2 2213/4885DPP4 120/4885PDE10A 1219/4885 |
| US-20090253689-A1 | Organic Compounds | OAT, GPR119, OTC | CNR2 2213/4885DPP4 120/4885PDE10A 1219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.