Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 4/20 | 0.34 |
| ▸ | DPP4 | P27487 | 5/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL340137 | 0.79 | DPP4 (0.39) | CRHR1DPP4DPP8DPP9CYP1A2 | |
| SCHEMBL339845 | 0.75 | DPP4 (0.32) | CRHR1DPP4DPP8 | |
| SCHEMBL339844 | 0.74 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL338489 | 0.74 | DPP4 (0.35) | CRHR1DPP4DPP8DPP9CYP1A2 | |
| SCHEMBL338576 | 0.73 | DPP4 (0.40) | DPP4DPP8DPP9CYP1A2CYP3A4 | |
| SCHEMBL339713 | 0.71 | DPP4 (0.40) | DPP4DPP8DPP9CYP1A2CYP3A4 | |
| SCHEMBL339105 | 0.71 | TDP1 (0.41) | DPP4DPP8 | |
| SCHEMBL340138 | 0.71 | DPP4 (0.41) | CRHR1DPP4DPP8DPP9CYP1A2 | |
| SCHEMBL339714 | 0.70 | DPP4 (0.45) | DPP4DPP8DPP9CYP1A2CYP3A4 | |
| SCHEMBL868834 | 0.70 | DPP4 (0.39) | DPP4DPP8DPP9CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077787-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2012-03-29 | — | — | US | disclosed |
| US-8097617-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-01-17 | — | — | US | disclosed |
| US-20090253689-A1 | Organic Compounds | NOVARTIS AG (CH) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077787-A1 | ORGANIC COMPOUNDS | OAT, GPR119, OTC | CRHR1 2644/4885DPP4 120/4885DPP8 403/4885 |
| US-20090253689-A1 | Organic Compounds | OAT, GPR119, OTC | CRHR1 2644/4885DPP4 120/4885DPP8 403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.