Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.56 |
| ▸ | XDH | P47989 | 1/20 | 0.51 |
| ▸ | ATR | Q13535 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266115 | 0.81 | MAPT (0.52) | ADORA2AADORA1XDHATRIDO1 | |
| SCHEMBL8740185 | 0.80 | IDO1 (0.51) | ADORA2AADORA1XDHATRIDO1 | |
| SCHEMBL2323257 | 0.80 | KDM4E (0.53) | ADORA2AADORA1ATRIDO1CCNT1 | |
| SCHEMBL30186623 | 0.80 | KDM4E (0.53) | ADORA2AADORA1ATRIDO1CCNT1 | |
| SCHEMBL11278322 | 0.78 | ALDH1A1 (0.58) | XDHATRIDO1PIK3CDPIK3CA | |
| SCHEMBL11265993 | 0.78 | F2RL3 (0.47) | ATRIDO1PIK3CDPIK3CAPIK3CG | |
| SCHEMBL1358158 | 0.78 | XDH (0.57) | ADORA2AADORA1XDHIDO1PIK3CD | |
| SCHEMBL3395696 | 0.78 | ADORA2A (0.53) | ADORA2AADORA1MAPT | |
| SCHEMBL2788482 | 0.77 | CCNT1 (0.63) | ADORA2AADORA1XDHATRIDO1 | |
| SCHEMBL2324638 | 0.76 | ADORA2A (0.53) | ADORA2AADORA1ATRIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |