Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 7/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28548702 | 0.89 | TSHR (0.53) | SCN9ABACE1MAOAARMAP4K4 | |
| SCHEMBL28912663 | 0.89 | TSHR (0.53) | SCN9ABACE1MAOAARMAP4K4 | |
| SCHEMBL3783934 | 0.87 | MAP4K4 (0.46) | SCN9ABACE1MAOAARMAP4K4 | |
| SCHEMBL28686237 | 0.86 | MAP4K4 (0.45) | SCN9ABACE1MAOAARMAP4K4 | |
| SCHEMBL672246 | 0.85 | TSHR (0.52) | SCN9ABACE1MAOAMAP4K4TSHR | |
| SCHEMBL3804592 | 0.85 | TSHR (0.68) | SCN9ABACE1MAOAMAP4K4TSHR | |
| SCHEMBL29805892 | 0.85 | BACE1 (0.51) | SCN9ABACE1ARTSHRGLA | |
| SCHEMBL29065978 | 0.85 | BACE1 (0.51) | SCN9ABACE1ARTSHRGLA | |
| SCHEMBL29521739 | 0.81 | MAOA (0.50) | MAOAMAP4K4TRPA1 | |
| SCHEMBL28301348 | 0.81 | MAOA (0.50) | MAOAMAP4K4TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023156485-A1 | TRIARYLALKYL BORATE SALTS AS COINITIATORS IN NIR PHOTOPOLYMER COMPOSITIONS | COVESTRO DEUTSCHLAND AG (DE) | 2023-08-24 | — | — | WO | disclosed |
| EP-3087072-A2 | SPIROINDOLINE ANTIPARASITIC DERIVATIVES | Zoetis Services LLC (US) | 2016-11-02 | — | — | EP | disclosed |
| US-20160296499-A1 | Spiroindoline Antiparasitic Derivatives | ZOETIS SERVICES LLC | 2016-10-13 | — | — | US | disclosed |
| CN-105829311-A | SPIROINDOLINE ANTIPARASITIC DERIVATIVES | 硕腾服务有限责任公司 | 2016-08-03 | — | — | CN | disclosed |
| WO-2015100232-A2 | SPIROINDOLINE ANTIPARASITIC DERIVATIVES | ZOETIS SERVICES LLC (US) | 2015-07-02 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| EP-1569896-B1 | TETRAHYDRO-NAPHTHALENE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-08-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160296499-A1 | Spiroindoline Antiparasitic Derivatives | PKD2, PKD1, AVPR2 | SCN9A 371/4885BACE1 4023/4885MAOA 1968/4885 |
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | SCN9A 4087/4885BACE1 925/4885MAOA 348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.