Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA5A | P35218 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.36 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.36 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6917671 | 0.81 | FABP4 (0.44) | PTGES2CA2CA1CA5ACA9 | |
| SCHEMBL5136326 | 0.81 | STAT3 (0.39) | PTGES2CA2CA1CA9STAT3 | |
| SCHEMBL14832067 | 0.76 | AR (0.42) | CYP3A4AR | |
| SCHEMBL3477005 | 0.73 | STAT3 (0.36) | PTGES2CA2CA1CA5ACA9 | |
| SCHEMBL302570 | 0.71 | MEN1 (0.56) | PTGES2CA2CA1CA5ACA9 | |
| SCHEMBL29418255 | 0.71 | MEN1 (0.56) | PTGES2CA2CA1CA5ACA9 | |
| SCHEMBL2777793 | 0.71 | CA2 (0.47) | PTGES2CA2CA1CA5ACA9 | |
| SCHEMBL11685314 | 0.71 | CA2 (0.50) | PTGES2CA2CA1CA5ACA9 | |
| SCHEMBL2512044 | 0.71 | CA2 (0.46) | PTGES2CA2CA1CA5ACA9 | |
| SCHEMBL8770175 | 0.71 | SCN9A (0.42) | PTGES2CA2CA1CA5ACA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245017-A2 | NOVEL HETEROCYCLES | Orchid Research Laboratories Limited (IN) | 2010-11-03 | — | — | EP | claimed |
| WO-2009095773-A2 | NOVEL HETEROCYCLES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2009-08-06 | — | — | WO | claimed |