Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP12 | P39900 | 2/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1177366 | 0.98 | MAPT (0.52) | MAPTALDH1A1GAALMNAKMT2A | |
| SCHEMBL1177288 | 0.93 | ALDH1A1 (0.51) | MAPTALDH1A1GAALMNAKMT2A | |
| Chloroacetic Acid SCHEMBL19183007 | 0.92 | ALDH1A1 (0.47) | MAPTALDH1A1GAALMNAKMT2A | |
| Trichloroacetic Acid SCHEMBL19183346 | 0.90 | ALDH1A1 (0.46) | MAPTALDH1A1GAALMNAKMT2A | |
| Dichloroacetic Acid SCHEMBL19183184 | 0.90 | ALDH1A1 (0.46) | MAPTALDH1A1GAALMNAKMT2A | |
| SCHEMBL1177415 | 0.89 | ALDH1A1 (0.54) | MAPTALDH1A1GAALMNAKMT2A | |
| SCHEMBL2533623 | 0.88 | MAPT (0.63) | MAPTALDH1A1GAALMNAKMT2A | |
| SCHEMBL10676527 | 0.84 | AGXT (0.50) | MAPTALDH1A1GAALMNAKMT2A | |
| SCHEMBL27790577 | 0.84 | ALDH1A1 (0.51) | MAPTALDH1A1GAALMNAKMT2A | |
| SCHEMBL1177416 | 0.84 | LMNA (0.48) | MAPTALDH1A1GAALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101896203-A | Use of solid forms of 5-aminolevulinic acid and derivatives in photodynamic therapy and diagnosis | PHOTOCURE ASA | 2010-11-24 | — | — | CN | claimed |
| CN-104524576-A | Use of aminolevulinic acid and derivatives thereof | PHOTOCURE ASA | 2015-04-22 | — | — | CN | disclosed |
| CN-104306968-A | Use of 5-aminolevulinic acid and derivatives in a solid form for photodynamic treatment and diagnosis | PHOTOCURE ASA | 2015-01-28 | — | — | CN | disclosed |
| CN-104069493-A | Use of aminolevulinic acid and derivatives thereof | PHOTOCURE ASA | 2014-10-01 | — | — | CN | disclosed |
| US-8546447-B2 | Treatment of acne using derivatives of 5-aminolevulinic acid | PHOTOCURE ASA (NO) | 2013-10-01 | — | — | US | disclosed |
| US-20130066256-A1 | Treatment of Acne Using Derivatives of 5-Aminolevulinic Acid | PHOTOCURE ASA (NO) | 2013-03-14 | — | — | US | disclosed |
| CN-101896203-A | Use of solid forms of 5-aminolevulinic acid and derivatives in photodynamic therapy and diagnosis | PHOTOCURE ASA | 2010-11-24 | — | — | CN | disclosed |
| EP-1814534-B1 | DERIVATIVES OF 5-AMINOLEVULINIC ACID FOR THE TREATMENT OF ACNE | PHOTOCURE ASA (NO) | 2010-06-02 | — | — | EP | disclosed |
| CN-101631541-A | Application of aminolevulinic acid and derivatives thereof | PHOTOCURE ASA | 2010-01-20 | — | — | CN | disclosed |
| US-20080188558-A1 | Treatment of Acne Using Derivatives of 5-Aminolevulinic Acid | PHOTOCURE ASA (NO) | 2008-08-07 | — | — | US | disclosed |
| EP-1814534-A1 | TREATMENT OF ACNE USING DERIVATIVES OF 5-AMINOLEVULINIC ACID | Photocure ASA (NO) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006051269-A1 | TREATMENT OF ACNE USING DERIVATIVES OF 5-AMINOLEVULINIC ACID | PHOTOCURE ASA (NO) | 2006-05-18 | — | — | WO | disclosed |