Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.31 |
| ▸ | WNT3A | P56704 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314965 | 1.00 | AXL (0.34) | AXLERN1TNKSCHEK2WNT3A | |
| SCHEMBL2413909 | 0.88 | ERN1 (0.34) | ERN1KDM4EFLT3SYKAURKB | |
| SCHEMBL2413910 | 0.88 | ERN1 (0.34) | ERN1KDM4EFLT3SYKAURKB | |
| SCHEMBL314409 | 0.86 | AXL (0.31) | AXL | |
| SCHEMBL314410 | 0.86 | AXL (0.31) | AXL | |
| SCHEMBL3400945 | 0.85 | CYP11B2 (0.36) | — | |
| SCHEMBL316049 | 0.85 | CYP11B2 (0.36) | — | |
| SCHEMBL2414743 | 0.84 | KMO (0.38) | ERN1KDM4E | |
| SCHEMBL2414741 | 0.84 | KMO (0.38) | ERN1KDM4E | |
| SCHEMBL316435 | 0.84 | ROCK2 (0.32) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |