Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | CA3 | P07451 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11290559 | 0.86 | ALDH1A1 (0.40) | HPGDPOLBHTTCA12CA1 | |
| SCHEMBL8858998 | 0.86 | ALDH1A1 (0.40) | HPGDPOLBHTTCA12CA1 | |
| SCHEMBL9787562 | 0.80 | ALDH1A1 (0.36) | HPGDPOLBHTTCHEK1CA12 | |
| SCHEMBL16875799 | 0.79 | LMNA (0.49) | HPGDPOLBHTTCA2ALDH1A1 | |
| SCHEMBL2011397 | 0.79 | LMNA (0.49) | HPGDCA2ALDH1A1KDM4ECYP2C19 | |
| SCHEMBL11300876 | 0.79 | KDM4E (0.35) | HPGDPOLBHTTCA12CA1 | |
| SCHEMBL3932936 | 0.78 | TPMT (0.37) | POLBCYP1A2CYP2C9 | |
| SCHEMBL9548344 | 0.78 | ALDH1A1 (0.40) | HPGDPOLBHTTCHEK1CA12 | |
| SCHEMBL8754983 | 0.78 | LMNA (0.37) | CYP2C19 | |
| SCHEMBL8357767 | 0.78 | CA12 (0.45) | HPGDHTTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245004-A2 | CONTRAST AGENTS | GE Healthcare AS (NO) | 2010-11-03 | — | — | EP | claimed |
| WO-2009106551-A2 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2009-09-03 | — | — | WO | claimed |