SCHEMBL339889

SCHEMBL339889

O=C(c1ccccc1)c1ccc(N2C(=O)C=CC2=O)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDAH1 O94760 1/20 0.69
MGLL Q99685 8/20 0.63
FAAH O00519 4/20 0.60
ALDH1A1 P00352 6/20 0.59
HSP90AA1 P07900 5/20 0.59
NPSR1 Q6W5P4 4/20 0.59
TDP1 Q9NUW8 3/20 0.59
PKM P14618 2/20 0.59
ATM Q13315 2/20 0.59
TLR9 Q9NR96 2/20 0.59
CCR6 P51684 1/20 0.59
MAPK1 P28482 1/20 0.53
HPGD P15428 2/20 0.53
TSHR P16473 2/20 0.53
HSD17B10 Q99714 2/20 0.53
NPC1 O15118 1/20 0.53
LMNA P02545 1/20 0.53
TP53 P04637 1/20 0.53
MAPT P10636 1/20 0.53
ALOX15 P16050 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL331470 0.92 DDAH1 (0.73) DDAH1MGLLFAAHALDH1A1HSP90AA1
SCHEMBL13584286 0.90 MGLL (0.73) DDAH1MGLLFAAHALDH1A1HSP90AA1
N-Ethylmaleimide SCHEMBL15130051 0.87 DDAH1 (0.54) DDAH1MGLLFAAHALDH1A1HSP90AA1
SCHEMBL6705392 0.86 DDAH1 (0.66) DDAH1MGLLFAAHALDH1A1HSP90AA1
SCHEMBL7799644 0.84 MGLL (0.60) DDAH1MGLLFAAHALDH1A1HSP90AA1
SCHEMBL28883435 0.83 MGLL (0.74) DDAH1MGLLFAAHALDH1A1HSP90AA1
SCHEMBL235166 0.82 DDAH1 (1.00) DDAH1MGLLFAAHALDH1A1HSP90AA1
SCHEMBL25278994 0.81 DDAH1 (0.59) DDAH1MGLLFAAHALDH1A1HSP90AA1
SCHEMBL28357228 0.81 DDAH1 (0.59) DDAH1MGLLFAAHALDH1A1HSP90AA1
SCHEMBL487019 0.81 MGLL (0.66) DDAH1MGLLFAAHALDH1A1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 837 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240052005-A1 IMPROVED CELL-PENETRATING PEPTIDES AND FUSION PROTEINS ANASTASIS BIOTEC LIMITED (GB) 2024-02-15 US claimed
EP-4263582-A1 IMPROVED CELL-PENETRATING PEPTIDES AND FUSION PROTEINS Anastasis Biotec Limited (GB) 2023-10-25 EP claimed
CN-116068167-A Separation and detection method of extracellular biomacromolecule 厦门福流生物科技有限公司 2023-05-05 CN claimed
CN-114437176-B Novel light labeling reagent and application thereof in cell surface proteome and N-glycosylation enrichment analysis 中国人民解放军军事科学院军事医学研究院 2022-12-13 CN claimed
WO-2022129926-A1 IMPROVED CELL-PENETRATING PEPTIDES AND FUSION PROTEINS ANASTASIS BIOTEC LIMITED (GB) 2022-06-23 WO claimed
CN-114437176-A Novel light labeling reagent and application thereof in cell surface proteome and N-glycosylation enrichment analysis 中国人民解放军军事科学院军事医学研究院 2022-05-06 CN claimed
CN-110649118-B Piece-splicing photovoltaic module 中节能太阳能科技(镇江)有限公司 2021-11-19 CN claimed
CN-111565707-A Devices and methods for delivering therapeutics 森玛治疗公司 2020-08-21 CN claimed
EP-3638205-A1 DEVICES AND METHODS FOR DELIVERING THERAPEUTICS Semma Therapeutics, Inc. (US) 2020-04-22 EP claimed
CN-110649118-A Piece-splicing photovoltaic module 中节能太阳能科技(镇江)有限公司 2020-01-03 CN claimed
US-20080199903-A1 Biological indicator STERIS INC. (US) 2008-08-21 US claimed
CN-101189519-A Biological indicator STERIS INC (US) 2008-05-28 CN claimed
EP-1886143-A1 BIOLOGICAL INDICATOR Steris, Inc. (US) 2008-02-13 EP claimed
WO-2007046865-A1 BIOLOGICAL INDICATOR STERIS, INC. (US) 2007-04-26 WO claimed
EP-1563306-B1 PHOTOLINKER MACROMOLECULES, METALLIC SUBSTRATES AND LIGANDS MODIFIED WITH SAID LINKERS, AND PROCESS OF PREPARATION THEREOF CSEM CT SUISSE ELECTRONIQUE (CH) 2007-02-14 EP claimed
US-20060269983-A1 Biological indicator AMERICAN STERILIZER COMPANY 2006-11-30 US claimed
CN-1149866-A Compounds containing michael-acceptor, especially maleimide or maleic acid derivatives, directly or indirectly linked to chromophore VANGUARD MEDICA LTD (GB) 1997-05-14 CN claimed
US-4342860-A AN UNSATUREATED IMIDE IS USED WITH A DI OR POLYISOCYANATE TO FORM A POLYIMIDE POLYMER RHONE-POULENC INDUSTRIES (FR) 1982-08-03 US claimed
US-4342861-A AN UNSATURATGED IMIDE AND A DI OR POLYISOCYANATE GO TO MAKE UP A POLYIMIDE POLYMER WHICH ALSO CONTAINS REPEATING AMIDE GROUPS RHONE-POULENC INDUSTRIES (FR) 1982-08-03 US claimed
US-4302572-A MOLDING MATERIALS; COATINGS; HEAT RESISTANCE; THIN FILMS RHONE-POULENC INDUSTRIES (FR) 1981-11-24 US claimed