SCHEMBL7799644

SCHEMBL7799644

O=C(c1ccccc1)c1cccc(N2C(=O)C=CC2=O)c1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 9/20 0.60
FAAH O00519 4/20 0.60
HSP90AA1 P07900 5/20 0.59
ALDH1A1 P00352 5/20 0.59
ATM Q13315 4/20 0.59
PKM P14618 3/20 0.59
HTT P42858 3/20 0.59
TDP1 Q9NUW8 2/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
NPSR1 Q6W5P4 3/20 0.54
CCR6 P51684 2/20 0.54
TLR9 Q9NR96 2/20 0.54
NSD2 O96028 1/20 0.53
G6PD P11413 1/20 0.53
KEAP1 Q14145 1/20 0.53
NFE2L2 Q16236 1/20 0.53
MAPT P10636 2/20 0.50
MITF O75030 1/20 0.50
MEN1 O00255 1/20 0.50
CYP1A2 P05177 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8530013 0.95 MGLL (0.67) MGLLFAAHHSP90AA1ALDH1A1ATM
SCHEMBL522308 0.86 NSD2 (0.67) MGLLFAAHHSP90AA1ALDH1A1ATM
SCHEMBL32670837 0.86 NSD2 (0.67) MGLLFAAHHSP90AA1ALDH1A1ATM
Hydrochloric Acid SCHEMBL4956408 0.84 NSD2 (0.65) MGLLFAAHHSP90AA1ALDH1A1ATM
SCHEMBL339889 0.84 DDAH1 (0.69) MGLLFAAHHSP90AA1ALDH1A1ATM
Hydrazine SCHEMBL16912716 0.83 NSD2 (0.62) MGLLFAAHHSP90AA1ALDH1A1ATM
SCHEMBL29510746 0.82 PARP1 (0.65) MGLLFAAHHSP90AA1ALDH1A1ATM
SCHEMBL10515423 0.82 PARP1 (0.65) MGLLFAAHHSP90AA1ALDH1A1ATM
SCHEMBL11023896 0.82 MGLL (0.64) MGLLFAAHHSP90AA1ALDH1A1ATM
SCHEMBL29065787 0.81 MGLL (0.53) MGLLFAAHHSP90AA1ALDH1A1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0599886-B1 MACROMONOMERS HAVING REACTIVE END GROUPS MISSISSIPPI POLYMER TECH INC (US) 2001-03-21 EP disclosed
US-5973075-A POLYPHENYL RESINS MAXDEM INCORPORATION (US) 1999-10-26 US disclosed
US-5827927-A Macromonomers having reactive end groups MAXDEM INCORPORATED (US) 1998-10-27 US disclosed
US-5824744-A RIGID POLYMER RODS AND MACROMONOMERS WITH REACTIVE END GROUPS FOR REINFORCEMENT MAXDEM INCORPORATED (US) 1998-10-20 US disclosed
US-5670564-A Macromonomers having reactive end groups MAXDEM INCORPORATED (US) 1997-09-23 US disclosed
EP-0599886-A4 MACROMONOMERS HAVING REACTIVE END GROUPS. MAXDEM INC (US) 1996-07-24 EP disclosed
EP-0599886-A1 MACROMONOMERS HAVING REACTIVE END GROUPS MAXDEM INCORPORATED (US) 1994-06-08 EP disclosed
WO-1993004099-A1 MACROMONOMERS HAVING REACTIVE END GROUPS MAXDEM INCORPORATED (US) 1993-03-04 WO disclosed