Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27613482 | 0.72 | NR1H2 (0.33) | — | |
| SCHEMBL5773612 | 0.71 | USP2 (0.38) | GPR119 | |
| SCHEMBL29250309 | 0.69 | USP2 (0.42) | GPR119 | |
| SCHEMBL27868546 | 0.69 | NR1H2 (0.36) | — | |
| SCHEMBL21219152 | 0.67 | BCHE (0.33) | — | |
| SCHEMBL31460174 | 0.66 | BCHE (0.33) | — | |
| SCHEMBL27771573 | 0.65 | BCHE (0.39) | GPR119 | |
| SCHEMBL28026573 | 0.63 | BCHE (0.35) | GPR119 | |
| SCHEMBL13803870 | 0.63 | NR1H2 (0.36) | GPR119 | |
| SCHEMBL1615448 | 0.62 | USP2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245014-A1 | UREA DERIVATIVES OF BENZOMORPHANES AND RELATED SCAFFOLDS, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE | Boehringer Ingelheim International GmbH (DE) | 2010-11-03 | — | — | EP | disclosed |
| WO-2009100872-A1 | UREA DERIVATIVES OF BENZOMORPHANES AND RELATED SCAFFOLDS, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-08-20 | — | — | WO | disclosed |